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科研机构
山东大学 [42]
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期刊论文 [42]
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2019 [5]
2018 [2]
2017 [3]
2016 [4]
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专题:山东大学
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Synthesis and structure-activity relationships of pyrazolo-[3,4-b]pyridine derivatives as adenosine 5'-monophosphate-activated protein kinase activators
期刊论文
ARCHIV DER PHARMAZIE, 2019, 卷号: 352, 期号: 8
作者:
Zheng, Bifeng
;
Peng, Yajun
;
Wu, Weihong
;
Ma, Junlong
;
Zhang, Yuzhao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/11
activator
AMPK
cell proliferation
molecular docking
pyrazolo[3
4-b]pyridine
Design, synthesis and antibacterial evaluation of novel 15-membered 11a-azahomoclarithromycin derivatives with the 1, 2, 3-triazole side chain
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 321-339
作者:
Qin, Yinhui
;
Teng, Yuetai
;
Ma, Ruixin
;
Bi, Fangchao
;
Liu, Zhiyang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
Macrolide antibiotics
Antibacterial activity
Resistant bacterial
strains
Structure-activity relationships
Indole: A privileged scaffold for the design of anti-cancer agents
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: 183
作者:
Wan Y.
;
Li Y.
;
Yan C.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Anti-Cancer
Drug design
Indole
Structure-activity relationships
Novel 2-arylthiopropanoyl-CoA inhibitors of alpha-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 92
作者:
Yevglevskis, Maksims
;
Nathubhai, Amit
;
Wadda, Katty
;
Lee, Guat L.
;
Al-Rawi, Suzanne
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/12/11
alpha-Methylacyl-CoA racemase (AMACR, P504S)
Branched-chain fatty acid
metabolism
Castrate-resistant prostate cancer (CRPC)
Drug
lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive
inhibition
Rational drug design
Structure-activity relationships
Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
Bioorganic Chemistry, 2019, 卷号: 92
作者:
Yevglevskis M.
;
Nathubhai A.
;
Wadda K.
;
Lee G.L.
;
Al-Rawi S.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/11
Branched-chain fatty acid metabolism
Castrate-resistant prostate cancer (CRPC)
Drug lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive inhibition
Rational drug design
Structure-activity relationships
α-Methylacyl-CoA racemase (AMACR, P504S)
Controllable 1D and 2D Cobalt Oxide and Cobalt Selenide Nanostructures as Highly Efficient Electrocatalysts for the Oxygen Evolution Reaction
期刊论文
CHEMISTRY-AN ASIAN JOURNAL, 2018, 卷号: 13, 期号: 18, 页码: 2700-2707
作者:
Zhang, Chenyun
;
Xin, Bingwei
;
Duan, Shengfu
;
Jiang, Anning
;
Zhang, Baohua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
cobalt
electrochemistry
selenium
structure-activity relationships
synthesis design
Cell Penetrating Peptides: A Promising Tool for the Cellular Uptake of Macromolecular Drugs
期刊论文
CURRENT PROTEIN & PEPTIDE SCIENCE, 2018, 卷号: 19, 期号: 2, 页码: 211-220
作者:
Zhu, Peipei
;
Jin, Lan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
Cell penetrating peptides
heparan sulfate proteoglycans
macromolecule
drugs
structure-activity relationships
cellular uptake mechanisms
electrostatic interaction
PD-1/PD-L1 Inhibitors for Immuno-oncology: From Antibodies to Small Molecules
期刊论文
CURRENT PHARMACEUTICAL DESIGN, 2017, 卷号: 23, 期号: 39, 页码: 6033-6041
作者:
Geng, Qiaohong
;
Jiao, Peifu
;
Jin, Peng
;
Su, Gaoxing
;
Dong, Jinlong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/16
Cancer immunotherapy
therapeutic antibody
small molecules
peptides
structure-activity relationships
tumor cells
Recent Advances in Synthetic -Glucosidase Inhibitors
期刊论文
CHEMMEDCHEM, 2017, 卷号: 12, 期号: 11, 页码: 819-829
作者:
Liu, Zhiyang
;
Ma, Shutao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/16
antidiabetic
biological activity
drug design
inhibitors
structure-activity relationships
Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 15, 页码: 3399-3402
作者:
Liu, Fang
;
Venter, Henrietta
;
Bi, Fangchao
;
Semple, Susan J.
;
Liu, Jingru
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
Antimicrobials
Biological evaluation
FtsZ
Structure-activity
relationships
5-Methylphenanthridium derivatives
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