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科研机构
山东大学 [8]
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期刊论文 [8]
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2019 [2]
2017 [1]
2011 [1]
2009 [1]
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专题:山东大学
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Novel 2-arylthiopropanoyl-CoA inhibitors of alpha-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 92
作者:
Yevglevskis, Maksims
;
Nathubhai, Amit
;
Wadda, Katty
;
Lee, Guat L.
;
Al-Rawi, Suzanne
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/12/11
alpha-Methylacyl-CoA racemase (AMACR, P504S)
Branched-chain fatty acid
metabolism
Castrate-resistant prostate cancer (CRPC)
Drug
lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive
inhibition
Rational drug design
Structure-activity relationships
Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents
期刊论文
Bioorganic Chemistry, 2019, 卷号: 92
作者:
Yevglevskis M.
;
Nathubhai A.
;
Wadda K.
;
Lee G.L.
;
Al-Rawi S.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/11
Branched-chain fatty acid metabolism
Castrate-resistant prostate cancer (CRPC)
Drug lipophilicity
Enzyme inhibitors
Ibuprofen
Mixed competitive inhibition
Rational drug design
Structure-activity relationships
α-Methylacyl-CoA racemase (AMACR, P504S)
Rational Design of a New Self-Codelivery System from Redox-Sensitive Camptothecin-Cytarabine Conjugate Assembly for Effectively Synergistic Anticancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2017, 卷号: 6, 期号: 24
作者:
He, Wenxiu
;
Hu, Xu
;
Jiang, Wei
;
Liu, Ruiling
;
Zhang, Di
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
camptothecin
chemotherapy
cytarabine
drug delivery
redox sensitive
Recent Advance in Aminopeptidase N (APN/CD13) Inhibitor Research
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2011, 卷号: 18, 期号: 32, 页码: 5011-5021
作者:
Zhang, X.
;
Fang, H.
;
Zhang, J.
;
Yuan, Y.
;
Xu, W.
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/23
Aminopeptidase N
rational drug design
inhibitors
peptidomimetics
anti-tumor
structure activity relationship
Impact of drug discovery on stem cell biology
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 卷号: 383, 期号: 3, 页码: 275-279
作者:
Zhang, Xiu-Zhen
;
Li, Xue-Juan
;
Ji, Hong-Fang
;
Zhang, Hong-Yu
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/26
Drug discovery
Stem cells
Rational design
Chemical biology
Strategies to overcome or circumvent P-glycoprotein mediated multidrug resistance
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2008, 卷号: 15, 期号: 5, 页码: 470-476
作者:
Yuan, Hongyu
;
Li, Xun
;
Wu, Jifeng
;
Li, Jinpei
;
Qu, Xianjun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/26
MDR
P-glycoprotein
cancer
P-glycoprotein modulators
rational drug
design
Aminopeptidase N (APN/CD13) as a Target for Anti-Cancer Agent Design
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2008, 卷号: 15, 期号: 27, 页码: 2850-2865
作者:
Zhang, Xiaopan
;
Xu, Wenfang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/26
Aminopeptidase N
APN/CD13
structure
inhibitors
anti-cancer agent
rational drug design
structure activity relationship
Structure-Activity Relationships and Rational Design Strategies for Radical-Scavenging Antioxidants
期刊论文
CURRENT COMPUTER-AIDED DRUG DESIGN, 2005, 卷号: 1, 期号: 3, 页码: 257-273
作者:
Zhang, Hong-Yu
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Antioxidant
radical
structure-activity relationship
rational design
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