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Rafoxanide, an organohalogen drug, triggers apoptosis and cell cycle arrest in multiple myeloma by enhancing DNA damage responses and suppressing the p38 MAPK pathway 期刊论文
Cancer letters, 2018, 卷号: 444, 页码: 45-59
作者:  Xiao, Wenqin;  Xu, Zhijian;  Chang, Shuaikang;  Li, Bo;  Yu, Dandan
收藏  |  浏览/下载:98/0  |  提交时间:2019/01/08
Identification of recurrent USP48 and BRAF mutations in Cushing's disease 期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:  Chen, Jianhua;  Jian, Xuemin;  Deng, Siyu;  Ma, Zengyi;  Shou, Xuefei
收藏  |  浏览/下载:117/0  |  提交时间:2019/01/08
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf(V600E) inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1059-1068
作者:  Wang, Gui-min;  Wang, Xiang;  Zhu, Jian-ming;  Guo, Bin-bin;  Yang, Zhuo
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
c-Myc Alteration Determines the Therapeutic Response to FGFR Inhibitors 期刊论文
CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 期号: 4, 页码: 974-984
作者:  Liu, Hongyan;  Ai, Jing;  Shen, Aijun;  Chen, Yi;  Wang, Xinyi
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf~(V600E) inhibitors 期刊论文
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 7, 页码: 1057-1068
作者:  Wang Guimin;  Wang Xiang;  Zhu Jianming;  Guo Binbin;  Yang Zhuo
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Repositioning organohalogen drugs: a case study for identification of potent B-Raf V600E inhibitors via docking and bioassay 期刊论文
Scientific Reports, 2016, 卷号: 6
作者:  Li, Yisu;  Guo, Binbin;  Xu, Zhijian;  Li, Bo;  Cai, Tingting
收藏  |  浏览/下载:9/0  |  提交时间:2019/01/08
Discovery of N-substituted 3-arylisoquinolone derivatives as antitumor agents originating from O-substituted 3-arylisoquinolines via [2,3] or [3,3] rearrangement 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 77, 页码: 204-210
作者:  Li, Bo;  Wang, Gaihong;  Xu, Zhijian;  Zhang, Yong;  Huang, Xiangui
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Overman rearrangement and Pomeranz-Fritsch reaction for the synthesis of benzoazepinoisoquinolones to discover novel antitumor agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 70, 页码: 677-684
作者:  Li, Bo;  Wang, Gaihong;  Yang, Mu;  Xu, Zhijian;  Zeng, Bubing
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Progress of anti-tumor study based on BRAF 期刊论文
Yao xue xue bao = Acta pharmaceutica Sinica, 2012, 卷号: 47, 期号: 12, 页码: 1567-74
作者:  Yan, Gui-Rui;  Xu, Zhi-Jian;  Wang, He-Yao;  Zhu, Wei-Liang
收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08
Combining pharmacophore, docking and substructure search approaches to identify and optimize novel B-Raf(V600E) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 17, 页码: 5428-5437
作者:  Xu, Zhijian;  Yan, Guirui;  Wang, Gaihong;  Li, Bo;  Zhu, Jianming
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08


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