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CORC

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Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：22/0  |  提交时间：2022/01/04
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载：93/0  |  提交时间：2021/11/04
Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma 期刊论文
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 417, 页码: 11
作者:  Geng, Huan;  Zhou, Mengxue;  Li, Bin;  Liu, Liang;  Yang, Xu
收藏  |  浏览/下载：24/0  |  提交时间：2021/08/17
NaNbO3-(Bi0.5Li0.5)TiO3 Lead-Free Relaxor Ferroelectric Capacitors with Superior Energy-Storage Performances via Multiple Synergistic Design 期刊论文
ADVANCED ENERGY MATERIALS, 2021, 页码: 12
作者:  Xie, Aiwen;  Zuo, Ruzhong;  Qiao, Zhenliang;  Fu, Zhengqian;  Hu, Tengfei
收藏  |  浏览/下载：66/0  |  提交时间：2021/08/17
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Zhou, Xiao-ru;  Li, Xiao;  Liao, Li-ping;  Han, Jie;  Huang, Jing
收藏  |  浏览/下载：30/0  |  提交时间：2021/06/11
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Zhou, Xiao-ru;  Li, Xiao;  Liao, Li-ping;  Han, Jie;  Huang, Jing
收藏  |  浏览/下载：27/0  |  提交时间：2021/06/11
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13
作者:  Gao, Feng;  Chen, Xiaoxu;  Lu, Junyan;  Hu, Shulei;  Xu, Hui
收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun;  Fu, Haoyu
收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:  Zhang, Ning;  Tian, Yu-Nan;  Zhou, Li-Na;  Li, Meng-Zhu;  Chen, Hua-Dong
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi
收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24

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