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科研机构
上海药物研究所 [67]
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期刊论文 [64]
会议论文 [3]
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2021 [4]
2020 [5]
2019 [3]
2018 [6]
2017 [9]
2016 [9]
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Oncology [1]
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DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation
期刊论文
DIABETES, 2021, 卷号: 70, 期号: 6, 页码: 1317-1333
作者:
Shuai, Lin
;
Li, Bo-Han
;
Jiang, Hao-Wen
;
Yang, Lin
;
Li, Jia
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
ZEB1 Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation Partly via Wnt/beta-Catenin Signaling
期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 卷号: 8, 页码: 11
作者:
Xu, Cuidi
;
Shi, Hongli
;
Jiang, Xin
;
Fan, Yongqian
;
Huang, Donghui
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/08/17
ZEB1
osteogenesis
Wnt/beta-catenin
postmenopausal osteoporosis
BMSCs
A lipid-soluble extract of Pinellia pedatisecta Schott orchestrates intratumoral dendritic cell-driven immune activation through SOCS1 signaling in cervical cancer
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 267, 页码: 10
作者:
Wang, Yumeng
;
Lu, Chong
;
Huang, Haixia
;
Yao, Sheng
;
Xu, Congjian
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
Cervical cancer
Tumor-associated dendritic cell (TADC)
Suppressor of cytokine signaling-1 (SOCS1)
JAK/STAT pathway
Immunotherapy
Traditional Chinese medicine
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma
期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:
Wang, Jianfeng
;
Wang, Chen
;
Xu, Pan
;
Li, Xiao
;
Lu, Yongning
收藏
  |  
浏览/下载:130/0
  |  
提交时间:2021/05/24
clear cell renal cell carcinoma
protein arginine methyltransferase 1
therapeutic
lipocalin2 (LCN2)
sunitinib
Design, Synthesis, and Biological Activities of Novel Triazolothiadiazole Derivatives Linked with Amino Side Chain Containing Urea Group as DOT1L Inhibitors
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 8, 页码: 2450-2459
作者:
Liu Na
;
Guo Siqi
;
Liu Junfang
;
Chen Yantao
;
Xu Xiaoming
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
DOT1L inhibitor
triazolothiadiazole
triazolothiadiazine
nucleophilic substitution
Structural Modifications of the Triazolo-thiadiazole Derivatives as DOT1L Inhibitors and Their Activities
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 5, 页码: 1345-1354
作者:
Xu Xiaoming
;
Guo Siqi
;
Zhang Jing
;
Chen Yantao
;
Kang Yaqing
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
DOT1L inhibitor
ttriazolo-thiadiazole
structural modification
hydrophobic substituent
structure-activity analysis
Downregulation of TET1 Promotes Bladder Cancer Cell Proliferation and Invasion by Reducing DNA Hydroxymethylation of AJAP1
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10, 页码: 16
作者:
Yan, Yi-lin
;
Huang, Zheng-nan
;
Zhu, Zhen
;
Cui, Yang-yan
;
Li, Mei-qian
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  |  
浏览/下载:84/0
  |  
提交时间:2020/12/24
ten-eleven translocation 1 (TET1)
DNA methylation
bladder cancer
vitamin C
adherens junction-associated protein 1 (AJAP1)
A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 252, 页码: 9
作者:
Cong, Jiaojiao
;
Ruan, Yiling
;
Lyu, Qinglin
;
Qin, Xiaohui
;
Qi, Xinming
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Aconitum alkaloids
Blood-brain barrier
Proton-coupled organic cation antiporter
hCMEC/D3 cells
Drug transport
pH-Sensitive Nano-Complexes Overcome Drug Resistance and Inhibit Metastasis of Breast Cancer by Silencing Akt Expression (vol 7, pg 4204, 2017)
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 5, 页码: 2399-2400
作者:
Yin, Jieying
;
Lang, Tianqun
;
Cun, Dongmei
;
Zheng, Zhong
;
Huang, Yan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
SNORD89 promotes stemness phenotype of ovarian cancer cells by regulating Notch1-c-Myc pathway
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 卷号: 17, 期号: 1, 页码: 15
作者:
Zhu, Wenjing
;
Niu, Jumin
;
He, Miao
;
Zhang, Liwen
;
Lv, Xuemei
收藏
  |  
浏览/下载:95/0
  |  
提交时间:2020/07/01
Ovarian cancer stem cells
TCGA
SNORNAs
SNORD89
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