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科研机构
上海药物研究所 [31]
内容类型
期刊论文 [31]
发表日期
2021 [1]
2020 [2]
2019 [2]
2018 [4]
2016 [3]
2015 [1]
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A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2021, 卷号: 13, 期号: 10, 页码: 11439-11449
作者:
Bu, Wenxuan
;
Li, Bo
;
Feng, Lijin
;
Feng, Qilin
;
Hu, Ke
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/16
Multiple myeloma
DCZ0858
mTOR
bone marrow microenvironment
cell proliferation
cell apoptosis
Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway
期刊论文
CIRCULATION RESEARCH, 2020, 卷号: 127, 期号: 4, 页码: 534-549
作者:
You, Yan
;
Bao, Wei-Lian
;
Zhang, Su-Lin
;
Li, Hai-Dong
;
Li, Hui
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/12/24
atherosclerosis
foam cell
lipid metabolism
monocytes
sorting nexin
Antitumor effects of rafoxanide in diffuse large B cell lymphoma via the PTEN/PI3K/Akt and JNK/c-Jun pathways
期刊论文
LIFE SCIENCES, 2020, 卷号: 243, 页码: 11
作者:
He, Wan
;
Xu, Zhijian
;
Song, Dongliang
;
Zhang, Hui
;
Li, Bo
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  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
Diffuse large B-cell lymphoma
Rafoxanide
PTEN/PI3K/AKT
Apoptosis
DNA damage
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression
期刊论文
CELL RESEARCH, 2019, 卷号: 29, 期号: 10, 页码: 787-803
作者:
Wang, Xinyi
;
Sun, Guangqiang
;
Feng, Teng
;
Zhang, Jing
;
Huang, Xun
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2020/07/01
Functional polymorphisms of the lncRNA H19 promoter region contribute to the cancer risk and clinical outcomes in advanced colorectal cancer
期刊论文
CANCER CELL INTERNATIONAL, 2019, 卷号: 19, 期号: 1, 页码: 12
作者:
Qin, Wenyan
;
Wang, Xiaodong
;
Wang, Yilin
;
Li, Yalun
;
Chen, Qiuchen
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
H19
Genetic polymorphisms
Susceptibility
Colorectal cancer
Prognosis
BLT1 in dendritic cells promotes Th1/Th17 differentiation and its deficiency ameliorates TNBS-induced colitis
期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2018, 卷号: 15, 期号: 12, 页码: 1047-1056
作者:
Zhou, Jinfeng
;
Lai, Weiming
;
Yang, Wanjie
;
Pan, Juping
;
Shen, Hu
收藏
  |  
浏览/下载:161/0
  |  
提交时间:2019/01/08
DCZ3301, a novel aryl-guanidino inhibitor, induces cell apoptosis and cell cycle arrest via suppressing the PI3K/AKT pathway in T-cell leukemia/lymphoma
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 7, 页码: 643-650
作者:
Xiao, Wenqin
;
Li, Bo
;
Sun, Xi
;
Yu, Dandan
;
Xie, Yongsheng
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/01/08
DCZ3301
T-cell leukemia/lymphoma
apoptosis
cell cycle
PI3K/AKT
Species-Specific Involvement of Integrin alpha IIb beta 3 in a Monoclonal Antibody CH12 Triggers Off-Target Thrombocytopenia in Cynomolgus Monkeys
期刊论文
MOLECULAR THERAPY, 2018, 卷号: 26, 期号: 6, 页码: 1457-1470
作者:
Zhang, Yiting
;
Sun, Jianhua
;
Tan, Minjia
;
Liu, Yongzhen
;
Li, Qian
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
dcz3301anovelarylguanidinoinhibitorinducescellapoptosisandcellcyclearrestviasuppressingthepi3kaktpathwayintcellleukemialymphoma
期刊论文
actabiochimicaetbiophysicasinica, 2018, 卷号: 50, 期号: 7, 页码: 643
作者:
Xiao Wenqin
;
Li Bo
;
Sun Xi
;
Yu Dandan
;
Xie Yongsheng
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
ACUTE LYMPHOBLASTIC-LEUKEMIA
NON-HODGKIN-LYMPHOMA
SIGNALING PATHWAYS
DEATH
PROTEIN
LINES
DCZ3301
T-cell leukemia/lymphoma
apoptosis
cell cycle
PI3K/AKT
Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation
期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2016, 卷号: 13, 期号: 3, 页码: 379-390
作者:
Wu, Yanwei
;
He, Shijun
;
Bai, Bingxin
;
Zhang, Luyao
;
Xue, Lu
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
B cell
plasma cell
SM934
systemic lupus erythematosus
Toll-like receptor
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