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科研机构
上海药物研究所 [10]
内容类型
期刊论文 [10]
发表日期
2020 [2]
2019 [2]
2018 [3]
2011 [2]
2008 [1]
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Discovery and characterization of natural products as novel indoleamine 2,3-dioxygenase 1 inhibitors through high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 423-431
作者:
Guo, Wei
;
Yao, Sheng
;
Sun, Pu
;
Yang, Tian-biao
;
Tang, Chun-ping
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
indoleamine 2
3-dioxygenase 1 inhibitor
natural product library
high-throughput fluorescence-based screening
discoveryandcharacterizationofnaturalproductsasnovelindoleamine23dioxygenase1inhibitorsthroughhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 423
作者:
Guo Wei
;
Yao Sheng
;
Sun Pu
;
Yang Tianbiao
;
Tang Chunping
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
indoleamine 2
3-dioxygenase 1 inhibitor
natural product library
high-throughput fluorescence-based screening
From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4 (vol 154, pg 44, 2018)
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 235-236
作者:
Gao, Ding-Ding
;
Dou, Hui-Xia
;
Su, Hai-Xia
;
Zhang, Ming-Ming
;
Wang, Ting
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 5, 页码: 30
作者:
Jia, Xiuwen
;
Li, Pinyi
;
Liu, Xiaoyan
;
Lin, Jiafu
;
Chu, Yiwen
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
amine nucleophiles
alkynoic acids
cascade reaction
gold catalysis
fused N-heterocycles
Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1902-1912
作者:
Gong, Grace Qun
;
Wang, Ke
;
Dai, Xin-Chuan
;
Zhou, Yan
;
Basnet, Rajesh
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
From hit to lead: Structure-based discovery of naphthalene-1 sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 44-59
作者:
Gao, Ding-Ding
;
Dou, Hui-Xia
;
Su, Hai-Xia
;
Zhang, Ming-Ming
;
Wang, Ting
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
FABP4 inhibitors
FABP3 sparing
Structure-based design strategy
X-ray crystallography
identificationstructuremodificationandcharacterizationofpotentialsmallmoleculesgk3inhibitorswithnovelscaffolds
期刊论文
中国药理学报英文版, 2018, 卷号: 039, 期号: 012, 页码: 1902
作者:
Grace Qun Gong
;
Ke Wang
;
XinChuan Dai
;
Yan Zhou
;
Rajesh Basnet
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
serum
and
glucocorticoid-regulated
kinase
SGK3
high-throughput
screening
inhibitors
molecular
modeling
Synthesis of 2-Phenylnaphthalenes through Gold-Catalyzed Dimerization via a Highly Selective Carbon Nucleophile Pathway
期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2011, 卷号: 76, 期号: 11, 页码: 4514-4521
作者:
Wang, Sinan
;
Zhang, Lei
;
Ding, Xiao
;
Zhou, Yu
;
Wang, Jinfang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Selective sp(3) C-H Bond Activation Based on a Carbocation Relay: Friedel-Crafts Reaction with Alkanes as the Alkylating Component
期刊论文
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2011, 期号: 2, 页码: 264-270
作者:
Wang, Jie
;
Zhou, Pengfei
;
Wang, Yang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
C-H activation
Friedel-Crafts reaction
Lewis acids
Carbocations
Alkanes
Alkylation
High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 6, 页码: 752-758
作者:
Yan, Jian-hua
;
Li, Qun-yi
;
Boutin, Jean A.
;
Renard, M. Pierre
;
Ding, Yi-xiang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
melanin-concentrating hormone
melanin-concentrating hormone receptor-1
antagonist
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