中国开放科研知识云: 检索

Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者: Lu, Shaoyong; He, Xinheng; Yang, Zhao; Chai, Zongtao; Zhou, Shuhua

收藏 | 浏览/下载：35/0 | 提交时间：2021/11/04

Exploring Conformational Change of Adenylate Kinase by Replica Exchange Molecular Dynamic Simulation 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 118, 期号: 5, 页码: 1009-1018
作者: Wang, Jinan; Peng, Cheng; Yu, Yuqu; Chen, Zhaoqiang; Xu, Zhijian

收藏 | 浏览/下载：42/0 | 提交时间：2020/07/01

Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 12
作者: Liu, Yuwei; Xue, Mengzhu; Du, Shaowei; Feng, Wanwan; Zhang, Ke

收藏 | 浏览/下载：29/0 | 提交时间：2020/07/01

Deciphering the role of dimer interface in intrinsic dynamics and allosteric pathways underlying the functional transformation of DNMT3A 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2018, 卷号: 1862, 期号: 7, 页码: 1667-1679
作者: Liang, Zhongjie; Hu, Junchi; Yan, Wenying; Jiang, Hualiang; Hu, Guang

收藏 | 浏览/下载：31/0 | 提交时间：2019/01/08

Conformational dynamics Allosteric communication Elastic network models, network theory, coevolution analysis

Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1673-1682
作者: Liu, Shi-en; Hu, Jun-chi; Zhang, Hao; Xu, Pan; Wan, Wei

收藏 | 浏览/下载：19/0 | 提交时间：2019/01/08

phosphoglycerate mutase 1 (PGAM1) human cancers metabolic target C-terminal region conformational changes molecular dynamics simulation

Two New Polymorphs of Huperzine A Obtained from Different Dehydration Processes of One Monohydrate 期刊论文
CRYSTAL GROWTH & DESIGN, 2016, 卷号: 16, 期号: 6, 页码: 3535-3542
作者: Zhang, Qi; Mei, Xuefeng

收藏 | 浏览/下载：12/0 | 提交时间：2019/01/08

Effects of drug-resistant mutations on the dynamic properties of HIV-1 protease and inhibition by Amprenavir and Darunavir 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者: Yu, Yuqi; Wang, Jinan; Shao, Qiang; Shi, Jiye; Zhu, Weiliang

收藏 | 浏览/下载：9/0 | 提交时间：2019/01/08

Helix Unfolding/Refolding Characterizes the Functional Dynamics of Staphylococcus aureus Clp Protease 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 卷号: 288, 期号: 24, 页码: 17643-17653
作者: Ye, Fei; Zhang, Jie; Liu, Hongchuan; Hilgenfeld, Rolf; Zhang, Ruihan

收藏 | 浏览/下载：20/0 | 提交时间：2019/01/08

Sampling the Conformational Energy Landscape of a Hyperthermophilic Protein by Engineering Key Substitutions 期刊论文
MOLECULAR BIOLOGY AND EVOLUTION, 2012, 卷号: 29, 期号: 6, 页码: 1683-1694
作者: Colletier, Jacques-Philippe; Aleksandrov, Alexey; Coquelle, Nicolas; Mraihi, Sonia; Mendoza-Barbera, Elena

收藏 | 浏览/下载：19/0 | 提交时间：2019/01/08

protein adaptation protein conformational energy landscape lactate dehydrogenase hyperthermophilic

Conformational transition of amyloid beta-peptide 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 卷号: 102, 期号: 15, 页码: 5403-5407
作者: Xu, YC; Shen, JJ; Luo, XM; Zhu, WL; Chen, KX

收藏 | 浏览/下载：10/0 | 提交时间：2019/01/08

molecular dynamics simulation

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