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科研机构
上海药物研究所 [14]
内容类型
期刊论文 [14]
发表日期
2021 [3]
2020 [2]
2019 [2]
2018 [1]
2017 [1]
2016 [2]
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BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 14
作者:
Feng, Mei
;
Wu, Zhongen
;
Zhou, Yan
;
Wei, Zhuang
;
Tian, Enming
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/11/04
PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10
作者:
Yang, Jun
;
Wang, Juan
;
Liu, Yuan
;
Zhang, Yu
;
Huang, Wenjing
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
Overcoming immune resistance by sequential prodrug nanovesicles for promoting chemoimmunotherapy of cancer
期刊论文
NANO TODAY, 2021, 卷号: 36, 页码: 12
作者:
Zhou, Fengqi
;
Gao, Jing
;
Xu, Zhiai
;
Li, Tianliang
;
Gao, Ang
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/06/11
Tumor microenvironment
Prodrug nanovesicles
Cancer immunotherapy
Immunogenic cell death
Adaptive immune resistance
Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
He, Zhi-di
;
Zhang, Meng
;
Wang, Yong-hui
;
He, Yang
;
Wang, Hai-rui
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
tumor-targeted delivery
immunogenic cell death
PD-1
PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint
Harnessing Genomic Stress for Antitumor Immunity
期刊论文
ANTIOXIDANTS & REDOX SIGNALING, 2020, 页码: 23
作者:
Pu, Congying
;
Tao, Siyao
;
Xu, Jun
;
Huang, Min
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
genomic stress
cancer
genomic instability
antitumor immunity
Identifying a ten-microRNA signature as a superior prognosis biomarker in colon adenocarcinoma
期刊论文
CANCER CELL INTERNATIONAL, 2019, 卷号: 19, 期号: 1, 页码: 16
作者:
Ma, Rong
;
Zhao, Yanyun
;
He, Miao
;
Zhao, Hongliang
;
Zhang, Yifan
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/07/01
Colon adenocarcinoma
MicroRNAs
Biomarker
Prognosis
Modelling liver cancer initiation with organoids derived from directly reprogrammed human hepatocytes
期刊论文
NATURE CELL BIOLOGY, 2019, 卷号: 21, 期号: 8, 页码: 1015-+
作者:
Sun, Lulu
;
Wang, Yuqing
;
Cen, Jin
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  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:
Zhang, Ning
;
Yu, Zhimei
;
Yang, Xiaohong
;
Zhou, Yan
;
Tang, Qing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Proliferation
Anticancer drug
Phosphatidylinositol 3-kinase inhibitor
Apoptosis
Structure-activity relationship
Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 5003-5015
作者:
Song, Qiaoling
;
Sun, Xiaoxiao
;
Guo, Hui
;
Yu, Qiang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
receptor tyrosine kinases
AKT
colorectal cancer
drug combination
RAS/RAF
Nuclear-targeting TAT-PEG-Asp(8)-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 8, 页码: 1110-1120
作者:
Pan, Zhen-zhen
;
Wang, Hui-yuan
;
Zhang, Meng
;
Lin, Ting-ting
;
Zhang, Wen-yuan
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
doxorubicin
multidrug resistance
cell-penetrating peptide
poly(aspartic acid)
intranuclear delivery
nanoparticles
human colon cancer HCT8/ADR cells
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