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科研机构
上海药物研究所 [10]
内容类型
期刊论文 [10]
发表日期
2021 [4]
2019 [1]
2018 [3]
2009 [1]
2008 [1]
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Impurity Identification and Scale-Up of a Novel Glycopeptide Antibiotic
期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2390-2402
作者:
Jiao, Shang
;
Guan, Dongliang
;
Xu, Lili
;
Liu, Bo
;
Shi, Weiwei
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/01/18
glycopeptide antibiotics
impurity
analytical method
process optimization and development
Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 45, 页码: 8
作者:
Shi, Weiwei
;
Chen, Feifei
;
Zou, Xiangman
;
Jiao, Shang
;
Wang, Siqi
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/08/17
Vancomycin analogues
LPS binding peptides
Vancomycin-Peptide Conjugates
Antibacterial activity
A facile method for vancomycin C-terminus functionalization and derivatization through hydrazide
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 42, 页码: 6
作者:
Hu, Yu
;
Zou, Xiangman
;
Shi, Weiwei
;
Ma, Chenhui
;
Chen, Feifei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/08/17
Vancomycin C-terminus modification
Hydrazide derivatives
Native Chemical Ligation
Antibacterial activity
Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 10
作者:
Fan, Yafei
;
Chen, Hangfei
;
Mu, Ning
;
Wang, Wengui
;
Zhu, Kongkai
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Nosiheptide analogues
Semi-synthesis
Antimicrobial activity
Molecular docking
Sulfonium, an Underestimated Moiety for Structural Modification, Alters the Antibacterial Profile of Vancomycin Against Multidrug-Resistant Bacteria
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 卷号: 58, 期号: 20, 页码: 6678-6682
作者:
Guan, Dongliang
;
Chen, Feifei
;
Qiu, Yunguang
;
Jiang, Bofeng
;
Gong, Likun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
antibacterial
multidrug-resistant bacteria
sulfonium
vancomycin
Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase Inhibitors with an Enhanced Safety Profile for the Treatment of MRSA, VISA, and LRSA Infections
期刊论文
ACS INFECTIOUS DISEASES, 2018, 卷号: 4, 期号: 3, 页码: 208-217
作者:
Li, Baoli
;
Ni, Shuaishuai
;
Chen, Feifei
;
Mao, Fei
;
Wei, Hanwen
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Staphylococcus aureus
diapophytoene desaturase
methicillin-resistant Staphylococcus aureus
hERG safety
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 1, 页码: 224-250
作者:
Li, Baoli
;
Ni, Shuaishuai
;
Mao, Fei
;
Chen, Feifei
;
Liu, Yifu
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Extra Sugar on Vancomycin: New Analogues for Combating Multidrug-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 1, 页码: 286-304
作者:
Guan, Dongliang
;
Chen, Feifei
;
Xiong, Lun
;
Tang, Feng
;
Faridoon
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Water-soluble phosphate prodrugs of pleuromutilin analogues with potent in vivo antibacterial activity against Gram-positive pathogens
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 18, 页码: 5407-5410
作者:
Fu, Liqiang
;
Jiang, Zhiteng
;
Cai, Zhan
;
Liu, Xin
;
He, Huili
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Pleuromutilin
Gram-positive bacteria
Water-soluble phosphate prodrugs
Synthesis and biological evaluation of new N-linked 5-triazolylmethyl oxazolidinones
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 8, 页码: 1706-1714
作者:
Fan, Houxing
;
Chen, Yilang
;
Jiang, Zhiteng
;
Zhang, Shuhua
;
Zhong, Dafang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
oxazolidinone
linezolid
antibacterial agents
gram-positive organisms
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