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科研机构
上海药物研究所 [139]
内容类型
期刊论文 [135]
会议论文 [3]
学位论文 [1]
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2021 [2]
2020 [8]
2019 [10]
2018 [14]
2017 [10]
2016 [7]
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The inhibitory effect of 225 frequently-used traditional Chinese medicines for CYP3A4 metabolic enzyme by isoform-specific probe
期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 5
作者:
Wei, Wenlong
;
Li, Zhenwei
;
Li, Hao-jv
;
An, Yaling
;
Qu, Hua
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/08/17
Inhibitory effect
Frequently-used traditional Chinese medicines
Isoform-specific probe
GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 2, 页码: 941-957
作者:
Wang, Congcong
;
Zhang, Yu-Fang
;
Guo, Shimeng
;
Zhao, Quan
;
Zeng, Yanping
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Selective and sensitive fluorescence imaging reveals microenvironment-dependent behavior of NO modulators in the endothelial system
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 5, 页码: 466-472
作者:
Dong, Ying
;
Li, Xiao-Rong
;
Li, Jia
;
Zang, Yi
;
Li, Xin
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2020/12/21
Nitric oxide modulator
Drug screen
Fluorescence imaging
Microenvironment
Endothelial cell
Anti-hepatitis B virus activity of swertisin isolated from Iris tectorum Maxim
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 257, 页码: 9
作者:
Xu, Hong-Yan
;
Ren, Ji-Hua
;
Su, Yu
;
Ren, Fang
;
Zhou, Yu-Jiao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
Iris tectorum Maxim
Swertisin
Hepatitis B virus
HBsAg
HBeAg
Quantitative analysis of fourteen bufadienolides in Venenum Bufonis crude drug and its Chinese patent medicines by ultra-high performance liquid chromatography coupled with tandem mass spectrometry
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 251, 页码: 8
作者:
Wei, Wen-long
;
An, Ya-ling
;
Zhang, Yan-zhi
;
Li, Zhen-wei
;
Zhou, Yang
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  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Venenum Bufonis
Multi-component quantification
Quality evaluation
UHPLC-QqQ-MS/MS
Pharmacophore-Based Virtual Screening Toward the Discovery of Novel Anti-echinococcal Compounds
期刊论文
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2020, 卷号: 10, 页码: 12
作者:
Liu, Congshan
;
Yin, Jianhai
;
Yao, Jiaqing
;
Xu, Zhijian
;
Tao, Yi
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
echinococcosis
Echinococcus multilocularis
pharmacophore modeling
virtual screenings
in vitro drug screen
cytotoxicity
E
multilocularis-infected mice
pharmacokinetics analysis
Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1
期刊论文
JOURNAL OF BREAST CANCER, 2020, 卷号: 23, 期号: 1, 页码: 20-35
作者:
Deng, Yu
;
Guo, Wanjun
;
Li, Guancheng
;
Li, Shuang
;
Li, Hong
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  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Breast neoplasms
C-terminal binding protein
Protocatechualdehyde
EPHA2 feedback activation limits the response to PDE delta inhibition in KRAS-dependent cancer cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 270-277
作者:
Chen, Yue-hong
;
Lv, Hao
;
Shen, Ning
;
Wang, Xiao-min
;
Tang, Shuai
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
KRAS
anticancer therapy
PDE delta
EPHA2
RAF
MEK
ERK signaling
Discovery of synergistic activity of fluoroquinolones in combination with antimicrobial peptides against clinical polymyxin-resistant Pseudomonas aeruginosa DK2
期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 2, 页码: 413-417
作者:
Zheng, Xinyu
;
Cao, Qiao
;
Cao, Qin
;
Mao, Fei
;
Li, Xiaokang
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Polymyxin B
Pseudomonas aeruginosa
Fluoroquinolones
Synergy
Cystic fibrosis
Antimicrobial peptides
Remodeling tumor immune microenvironment (TIME) for glioma therapy using multi-targeting liposomal codelivery
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 卷号: 8, 期号: 2, 页码: 16
作者:
Zheng, Zening
;
Zhang, Jiaxin
;
Jiang, Jizong
;
He, Yang
;
Zhang, Wenyuan
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  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
tumor microenvironment
macrophages
brain neoplasms
immunotherapy
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