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科研机构
上海药物研究所 [10]
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期刊论文 [10]
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2021 [1]
2017 [2]
2016 [4]
2014 [1]
2013 [1]
2009 [1]
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Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
Physiological oxygen tension reduces hepatocyte dedifferentiation in in vitro culture
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Guo, Ren
;
Xu, Xinxiu
;
Lu, Yuting
;
Xie, Xin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Fabrication of stable galactosylated alginate microcapsules via covalent coupling onto hydroxyl groups for hepatocytes applications
期刊论文
CARBOHYDRATE POLYMERS, 2017, 卷号: 155, 页码: 456-465
作者:
Lou, Ruyun
;
Yu, Weiting
;
Song, Yizhe
;
Ren, Ying
;
Zheng, Huizhen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Galactosylated alginate
Hydroxyl groups
Microcapsules
Primary hepatocytes
Biological artificial liver support systems
Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model
期刊论文
Scientific Reports, 2016, 卷号: 6
作者:
Ni, Xuan
;
Gao, Yimeng
;
Wu, Zhitao
;
Ma, Leilei
;
Chen, Chen
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Comprehensive Evaluation of the Metabolism of Genipin-1-beta-D-gentiobioside in Vitro and in Vivo by Using HPLC-Q-TOF
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2016, 卷号: 64, 期号: 27, 页码: 5490-5498
作者:
Jiang, Pei
;
Ma, Yuanjie
;
Gao, Yu
;
Li, Zhixiong
;
Lian, Shan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
genipin-1-beta-D-gentiobioside
metabolite
in vitro
in vivo
HPLC-Q-TOF
Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 25, 页码: 38091-38104
作者:
Wang, Ying
;
Zhan, Zhengsheng
;
Jiang, Xifei
;
Peng, Xia
;
Shen, Yanyan
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
c-Met
kinase inhibitor
Simm530
Optimized Hepatocyte-Like Cells with Functional Drug Transporters Directly-Reprogrammed from Mouse Fibroblasts and their Potential in Drug Disposition and Toxicology
期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 卷号: 38, 期号: 5, 页码: 1815-1830
作者:
Wu, Zhi-Tao
;
Yao, Dan
;
Ji, Shu-Yi
;
Ni, Xuan
;
Gao, Yi-Meng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Direct reprogramming
Hepatocyte-like cells
Hepatic transporters
Biliary clearances
Cholestasis
SOMG-833, a Novel Selective c-MET Inhibitor, Blocks c-MET-Dependent Neoplastic Effects and Exerts Antitumor Activity
期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, 卷号: 350, 期号: 1, 页码: 36-45
作者:
Zhang, Hao-tian
;
Wang, Lu
;
Ai, Jing
;
Chen, Yi
;
He, Chang-xi
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
Effects of glucose and insulin on expression and function of bile acid transporters in sandwich cultured rat hepatocytes
期刊论文
Chinese Journal of Clinical Pharmacology and Therapeutics, 2013, 卷号: 18, 期号: 8, 页码: 847-852
作者:
He Lei
;
Guo Cen
;
Yao Dan
;
Sheng Jingjing
;
Pan Guoyu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Glucose
Insulin
Sandwich cultured rat hepatocyte
Bile acid transporter
The relationship between diphenylamine structure and NSAIDs-induced hepatocytes injury
期刊论文
TOXICOLOGY LETTERS, 2009, 卷号: 186, 期号: 2, 页码: 111-114
作者:
Li, Yan
;
Qi, Xin-ming
;
Xue, Xiang
;
Wu, Xiong-fei
;
Wu, Yuan-feng
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Mitochondria
Liver injury
NSAIDs
Diphenylamine structure
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