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Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases 期刊论文
CANCER LETTERS, 2022, 卷号: 525, 页码: 170-178
作者:  Su, Shang;  Cao, Jingchen;  Meng, Xiangqi;  Liu, Ruihua;  Vander Ark, Alexandra
收藏  |  浏览/下载:53/0  |  提交时间:2022/01/04
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载:62/0  |  提交时间:2022/01/18
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载:30/0  |  提交时间:2021/12/16
Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 906, 页码: 8
作者:  Xiao, Meng-Chao;  Qian, Hui;  Huang, Chen-Kai;  Zheng, Bai-Nan;  Yan, Fang-Zhi
收藏  |  浏览/下载:50/0  |  提交时间:2021/11/04
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020) 期刊论文
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载:58/0  |  提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:  Zhang,Tao;  Qu,Rong;  Chan,Shingpan;  Lai,Mengzhen;  Tong,Linjiang
收藏  |  浏览/下载:41/0  |  提交时间:2021/11/04
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
收藏  |  浏览/下载:47/0  |  提交时间:2021/08/17
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Liu, Lu;  Li, Wei;  Yang, Le;  Guo, Zi-tao;  Xue, Hao
收藏  |  浏览/下载:78/0  |  提交时间:2021/08/17
Intestinal MYC modulates obesity-related metabolic dysfunction 期刊论文
NATURE METABOLISM, 2021, 页码: 37
作者:  Luo, Yuhong;  Yang, Shoumei;  Wu, Xuan;  Takahashi, Shogo;  Sun, Lulu
收藏  |  浏览/下载:30/0  |  提交时间:2021/08/17
Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 7, 页码: 1885-1902
作者:  Wu, Xu;  Yin, Chun;  Ma, Jiang;  Chai, Stella;  Zhang, Chunyuan
收藏  |  浏览/下载:39/0  |  提交时间:2021/11/04


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