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CORC

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The discovery of a novel series of potential ERR alpha inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo 期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 125-134
作者:  Gao, Zhipei;  Wang, Tianxiao;  Li, Rui;  Du, Yongli;  Lv, Han
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/18
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo
收藏  |  浏览/下载：42/0  |  提交时间：2022/01/18
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/04
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：86/0  |  提交时间：2021/11/04
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/01
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction 期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:  Xiong, Jiacheng;  Xiang, Yusen;  Huang, Ziming;  Liu, Xiaohong;  Wang, Mengge
收藏  |  浏览/下载：39/0  |  提交时间：2021/12/01
A hybrid framework for improving uncertainty quantification in deep learning-based QSAR regression modeling 期刊论文
JOURNAL OF CHEMINFORMATICS, 2021, 卷号: 13, 期号: 1, 页码: 17
作者:  Wang, Dingyan;  Yu, Jie;  Chen, Lifan;  Li, Xutong;  Jiang, Hualiang
收藏  |  浏览/下载：59/0  |  提交时间：2021/11/04
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1) 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:  Yu Lijie;  Feng Bo;  Wang Zhijia;  Gao Lixin;  Zhang Chun
收藏  |  浏览/下载：195/0  |  提交时间：2021/11/04
Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 32, 页码: 8
作者:  Wang, Xi;  Cheng, Xi;  Zhao, Lihua;  Wang, Yuzhe;  Ye, Chenyu
收藏  |  浏览/下载：24/0  |  提交时间：2021/11/04
Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor 期刊论文
ELIFE, 2021, 卷号: 10, 页码: 20
作者:  Zhao, Fenghui;  Zhang, Chao;  Zhou, Qingtong;  Hang, Kaini;  Zou, Xinyu
收藏  |  浏览/下载：36/0  |  提交时间：2021/08/17

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