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科研机构
上海药物研究所 [403]
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期刊论文 [395]
会议论文 [5]
学位论文 [3]
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2021 [9]
2020 [10]
2019 [12]
2018 [23]
2017 [22]
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Biochemist... [4]
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A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Fast determination of 16 circulating neurotransmitters and their metabolites in plasma samples of spontaneously hypertensive rats intervened with five different Uncaria
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1179, 页码: 9
作者:
Gao, Lei
;
Zhang, Zijia
;
Feng, Zijin
;
Wei, Wenlong
;
Wu, Wenyong
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
Neurotransmitters
LC-MS
Hypertension
Uncaria
Spontaneously hypertensive rats
Scale-Up Preparation of Crocins I and II from Gardenia jasminoides by a Two-Step Chromatographic Approach and Their Inhibitory Activity Against ATP Citrate Lyase
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 11, 页码: 11
作者:
Guan, Shuguang
;
Pu, Qiaoli
;
Liu, Yinan
;
Wu, Honghong
;
Yu, Wenbo
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/08/17
crocins
preparation method
macroporous resin column chromatography
high-speed counter-current chromatography
inhibitory activity on ATP citrate lyase
Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7
作者:
Pan, Lu-lu
;
Chen, Tao
;
Hui, Min
;
Wang, Shuo
;
Fu, Li
收藏
  |  
浏览/下载:128/0
  |  
提交时间:2021/05/24
LC-MS/MS
Forsythin
Aglycone glucuronide
Aglycone sulfate
Pharmacokinetics
Determination of maytansinoids in Trewia nudiflora using QuEChERS extraction combined with HPLC
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7
作者:
Li, Ya-Nan
;
Li, Jia-Nan
;
Ouyang, Qin
;
Zhou, Yu-Bo
;
Lei, Chun
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
Trewia nudiflora
QuEChERS method
Maytansinoids
HPLC
Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC-MS/MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 194, 页码: 10
作者:
Hu, Wenjuan
;
Chang, Lu
;
Ke, Changqiang
;
Xie, Yuanchao
;
Shen, Jingshan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Remdesivir
Nucleotide monophosphate
Nucleotide triphosphate
Stability
Recovery
LC-MS/MS
Comprehensive evaluation of NAODESHENG by combining UPLC quantitative fingerprint and antioxidant activity
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 193, 页码: 7
作者:
Liao, Jun-cheng
;
Wu, Yun-shan
;
Xu, Fang-fang
;
Chen, Wei-ying
;
Zheng, Zuo-liang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Determination of content
NAODESHENG
Multi-wavelength fusion fingerprint
Anti-oxidation
Traditional Chinese Medicine (TCM)
Characterization and quantitative determination of henagliflozin metabolites in humans
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:
Chen, Zhendong
;
Li, Liang
;
Zhan, Yan
;
Zhang, Yifan
;
Liu, Haiyan
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
Henagliflozin
Metabolism
LC-MS/MS
Rapid Determination of 3 Components With Different Polarities in Medicinal Mushrooms by Multistep Matrix Solid-Phase Dispersion and High-Performance Liquid Chromatography Analysis
期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2021, 卷号: 16, 期号: 1, 页码: 7
作者:
Qian, Zhengming
;
Wu, Zi
;
Li, Chunhong
;
Yao, ChangLiang
;
Tan, Guoying
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/05/24
matrix solid-phase dispersion
mannitol
adenosine
ergosterol
medicinal mushrooms
Offline two-dimensional liquid chromatography coupled with ion mobility-quadrupole time-of-flight mass spectrometry enabling four-dimensional separation and characterization of the multicomponents from white ginseng and red ginseng
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 6, 页码: 597-609
作者:
Zuo, Tiantian
;
Zhang, Chunxia
;
Li, Weiwei
;
Wang, Hongda
;
Hu, Ying
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Dimension-enhanced strategy
Multicomponent characterization
Ginsenoside
Offline two-dimensional liquid chromatography
Ion mobility-quadrupole time-of-flight mass spectrometry
In-house database
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