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科研机构
西安交通大学 [9]
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期刊论文 [9]
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2019 [1]
2018 [1]
2017 [2]
2016 [2]
2013 [1]
2012 [1]
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The Third-Generation EGFR Inhibitor, Osimertinib, Promotes c-FLIP Degradation, Enhancing Apoptosis Including TRAI-Induced Apoptosis in NSCL Cells with Activating EGFR Mutations
期刊论文
TRANSLATIONAL ONCOLOGY, 2019, 卷号: 12, 页码: 705-713
作者:
Shi, Puyu
;
Zhang, Shuo
;
Zhu, Lei
;
Qian, Guoging
;
Ren, Hui
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/11/19
Synthesis and evaluation of 2,9-disubstituted 8-phenylthio/phenylsulfinyl-9H-purine as new EGFR inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 页码: 2173-2185
作者:
Hei, Yuan-Yuan
;
Shen, Ying
;
Wang, Jin
;
Zhang, Hao
;
Zhao, Hong-Yi
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/26
Antiproliferative effects
Drug design
EGFR-TK inhibitor
Anticancer agent
Purine
A case report of EGFR mutant lung adenocarcinoma that acquired resistance to EGFR-tyrosine kinase inhibitors with T790M mutation and epithelial-to-mesenchymal transition.
期刊论文
Respiratory medicine case reports, 2017, 卷号: 22, 页码: 183-186
作者:
Zhang Nana
;
Wang Depu
;
Li Xiaofeng
;
Yang Zhe
;
Zhang Guanjun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
EGFR-TKI resistance
Epidermal growth factor receptor tyrosine kinase inhibitor
Epithelial-to-mesenchymal transition
Secondary mutation
Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation
期刊论文
CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 页码: 6567-6579
作者:
Shi, Puyu
;
Oh, You-Take
;
Deng, Liang
;
Zhang, Guojing
;
Qian, Guoqing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling
期刊论文
CANCER CELL, 2016, 卷号: 29, 期号: [db:dc_citation_issue], 页码: 639-652
作者:
Zhang, Xing-Ding
;
Baladandayuthapani, Veerabhadran
;
Lin, Heather
;
Mulligan, George
;
Li, Bin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/02
Combination of 4-anilinoquinazoline, arylurea and tertiary amine moiety to discover novel anticancer agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: [db:dc_citation_issue], 页码: 179-190
作者:
Zuo, Sai-Jie
;
Zhang, Sai
;
Mao, Shuai
;
Xie, Xiao-Xiao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/02
Diaryl urea
Tertiary amine
Anticancer agent
Gefitinib
EGFR-TK inhibitor
Discovery of 2-aryl-8-hydroxy (or methoxy)-isoquinolin-1(2H)-ones as novel EGFR inhibitor by scaffold hopping
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: [db:dc_citation_issue], 页码: 6956-6964
作者:
Kang, Bo-Rui
;
Shan, Ai-Lin
;
Li, Yi-Ping
;
Xu, Jing
;
Lu, She-Min
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/10
2-Arylisoquinolin-1(2H)-ones
Scaffold hoping
Antiproliferative activity
EGFR inhibitor
Synthesis
Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC-EGFR dual inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: [db:dc_citation_issue], 页码: 4405-4412
作者:
Zuo, Miao
;
Zheng, Yue-Wen
;
Lu, She-Min
;
Li, Yan
;
Zhang, San-Qi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/10
HDAC inhibitor
Synthesis
Antiproliferative activity
EGFR inhibitor
N-Aryl salicylamides
Antitumor Activity of Taspine by Modulating the EGFR Signaling Pathway of Erk1/2 and Akt In Vitro and In Vivo
期刊论文
PLANTA MEDICA, 2011, 卷号: 77, 期号: [db:dc_citation_issue], 页码: 1774-1781
作者:
Zhang, Yanmin
;
Zheng, Lei
;
Zhang, Jie
;
Dai, Bingling
;
Wang, Nan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/10
taspine
EGFR inhibitor
EGFR
signaling pathway
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