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The Third-Generation EGFR Inhibitor, Osimertinib, Promotes c-FLIP Degradation, Enhancing Apoptosis Including TRAI-Induced Apoptosis in NSCL Cells with Activating EGFR Mutations 期刊论文
TRANSLATIONAL ONCOLOGY, 2019, 卷号: 12, 页码: 705-713
作者:  Shi, Puyu;  Zhang, Shuo;  Zhu, Lei;  Qian, Guoging;  Ren, Hui
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/19
Synthesis and evaluation of 2,9-disubstituted 8-phenylthio/phenylsulfinyl-9H-purine as new EGFR inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 页码: 2173-2185
作者:  Hei, Yuan-Yuan;  Shen, Ying;  Wang, Jin;  Zhang, Hao;  Zhao, Hong-Yi
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/26
A case report of EGFR mutant lung adenocarcinoma that acquired resistance to EGFR-tyrosine kinase inhibitors with T790M mutation and epithelial-to-mesenchymal transition. 期刊论文
Respiratory medicine case reports, 2017, 卷号: 22, 页码: 183-186
作者:  Zhang Nana;  Wang Depu;  Li Xiaofeng;  Yang Zhe;  Zhang Guanjun
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/26
Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation 期刊论文
CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 页码: 6567-6579
作者:  Shi, Puyu;  Oh, You-Take;  Deng, Liang;  Zhang, Guojing;  Qian, Guoqing
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/26
Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling 期刊论文
CANCER CELL, 2016, 卷号: 29, 期号: [db:dc_citation_issue], 页码: 639-652
作者:  Zhang, Xing-Ding;  Baladandayuthapani, Veerabhadran;  Lin, Heather;  Mulligan, George;  Li, Bin
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/02
Combination of 4-anilinoquinazoline, arylurea and tertiary amine moiety to discover novel anticancer agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: [db:dc_citation_issue], 页码: 179-190
作者:  Zuo, Sai-Jie;  Zhang, Sai;  Mao, Shuai;  Xie, Xiao-Xiao
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/02
Discovery of 2-aryl-8-hydroxy (or methoxy)-isoquinolin-1(2H)-ones as novel EGFR inhibitor by scaffold hopping 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: [db:dc_citation_issue], 页码: 6956-6964
作者:  Kang, Bo-Rui;  Shan, Ai-Lin;  Li, Yi-Ping;  Xu, Jing;  Lu, She-Min
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/10
Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC-EGFR dual inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: [db:dc_citation_issue], 页码: 4405-4412
作者:  Zuo, Miao;  Zheng, Yue-Wen;  Lu, She-Min;  Li, Yan;  Zhang, San-Qi
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/10
Antitumor Activity of Taspine by Modulating the EGFR Signaling Pathway of Erk1/2 and Akt In Vitro and In Vivo 期刊论文
PLANTA MEDICA, 2011, 卷号: 77, 期号: [db:dc_citation_issue], 页码: 1774-1781
作者:  Zhang, Yanmin;  Zheng, Lei;  Zhang, Jie;  Dai, Bingling;  Wang, Nan
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/10


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