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上海药物研究所 [190]
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期刊论文 [702]
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Pharmacology and anti-addiction effects of the novel kappa opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A
期刊论文
出版物, 3111, 期号: 0, 页码: 1-53
作者:
B Simonson
;
A S Morani
;
A W M Ewald
;
L Walker
;
N Kumar
收藏
  |  
浏览/下载:138/0
  |  
提交时间:2017/07/24
Methadone switching for refractory cancer pain
期刊论文
BMC PALLIATIVE CARE, 2022, 卷号: 21
作者:
Ding, Haiying
;
Song, Yu
;
Xin, Wenxiu
;
Sun, Jiao
;
Zhong, Like
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/23
Methadone
Refractory cancer pain
Efficacy
Safety
Cost
Opioids switching
Impact of individualized pharmaceutical care on efficacy and safety of opioid-tolerant outpatients with cancer pain: a multicenter randomized controlled trial
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2022
作者:
Ding, Haiying
;
Song, Yu
;
Wu, Nan
;
Zheng, Xiaowei
;
Wei, Qing
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/12/22
Cancer pain
pharmacists
pharmaceutical service
opioids
outpatients
The role of hippocampus in memory reactivation: an implication for a therapeutic target against opioid use disorder
期刊论文
CURRENT ADDICTION REPORTS, 2022, 页码: 13
作者:
Dai, Zhong-hua
;
Xu, Xing
;
Chen, Wei-qi
;
Nie, Li-na
;
Liu, Ying
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  |  
浏览/下载:74/0
  |  
提交时间:2022/03/28
opioid withdrawal
memory reactivation
extinction
hippocampus
noradrenergic signaling
Dezocine as a potent analgesic: overview of its pharmacological characterization
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Ye, Rong-Rong
;
Jiang, Shuang
;
Xu, Xu
;
Lu, Yan
;
Wang, Yu-Jun
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  |  
浏览/下载:30/0
  |  
提交时间:2021/12/16
dezocine
opioid receptors
norepinephrine
serotonin transporter
postoperative pain
anesthesia
Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence
期刊论文
CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21
作者:
Zan, Gui-Ying
;
Wang, Yu-Jun
;
Li, Xue-Ping
;
Fang, Jun-Fan
;
Yao, Song-Yu
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/12/16
Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Wei, Yuan-yuan
;
Ma, Yan
;
Yao, Song-yu
;
Kong, Ling-hui
;
Liu, Xiao
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/11/04
kappa-opioid receptor agonist
4,5-expoxymorphinan
antinociception
conditioned place aversion
sedation
U50,488H
morphine
Nor-BNI
beta-FNA
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:
He, Qian
;
Wei, Yuanyuan
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  |  
浏览/下载:88/0
  |  
提交时间:2021/11/04
Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483
作者:
Huang, Huoming
;
Li, Xueping
;
Xie, Peng
;
Li, Xinwei
;
Xu, XueJun
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/08/17
Amygdala dynorphin/kappa opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zan, Gui-ying
;
Sun, Xiang
;
Wang, Yu-jun
;
Liu, Rui
;
Wang, Chen-yao
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
depression
social defeat stress
amygdala
κ
opioid receptor
dynorphin
c-fos
ERK
norBNI
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