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CORC

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2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:  Hu, Xianglong;  Xun, Qiuju;  Zhang, Tao;  Zhu, Su-Jie;  Li, Qian
收藏  |  浏览/下载：46/0  |  提交时间：2020/07/01
Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands 期刊论文
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463
作者:  Qian, Hai-Yan;  Wang, Zhi-Long;  Chen, Li-Li;  Pan, You-Lu;  Xie, Xiao-Yu
收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08
Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 6, 页码: 2353-2371
作者:  Xun, Qiuju;  Zhang, Zhang;  Luo, Jinfeng;  Tong, Linjiang;  Huang, Minhao
收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08
Synthesis and structure-activity relationship study of pyrazolo[3,4-d]pyrimidines as tyrosine kinase RET inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2544-2548
作者:  Wang, Chengyan;  Liu, Hongchun;  Song, Zilan;  Ji, Yinchun;  Xing, Li
收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08
Design, Synthesis and Anti-Proliferative Activities of 2,6-Substituted Thieno[3,2-d] pyrimidine Derivatives Containing ElectrophilicWarheads 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 5
作者:  Zhang, Qiumeng;  Hu, Zonglong;  Shen, Qianqian;  Chen, Yi;  Lu, Wei
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 17, 页码: 7856-7876
作者:  Golani, Lalit K.;  Wallace-Povirk, Adrianne;  Deis, Siobhan M.;  Wong, Jennifer;  Ke, Jiyuan
收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08
2,4-Diarylamino-pyrimidines as kinase inhibitors co-targeting IGF1R and EGFR(L858R/T790M) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 19, 页码: 4277-4281
作者:  Chan, Shingpan;  Han, Kun;  Qu, Rong;  Tong, Linjiang;  Li, Yingjun
收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08
Design, synthesis and biological evaluation of 4-anilinothieno[2,3-d]pyrimidine-based hydroxamic acid derivatives as novel histone deacetylase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 21, 页码: 6146-6155
作者:  Yang, Wei;  Li, Lixuan;  Ji, Xun;  Wu, Xiaowei;  Su, Mingbo
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
Microwave Assisted Tandem Heck-Sonogashira Reactions of N,N-Di-Boc-Protected 6-Amino-5-iodo-2-methyl Pyrimidin-4-ol in An Efficient Approach to Functionalized Pyrido[2,3-d]Pyrimidines 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 13, 页码: 3524-3527
作者:  Liu, Yang;  Jin, Shiyu;  Wang, Zi;  Song, Linhua;  Hua, Youhong
收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08
Design, synthesis and biological evaluation of novel 6-alkenylamides substituted of 4-anilinothieno[2,3-d]pyrimidines as irreversible epidermal growth factor receptor inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 7, 页码: 2366-2378
作者:  Ji, Xun;  Peng, Ting;  Zhang, Xu;  Li, Jian;  Yang, Wei
收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08

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