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科研机构
上海药物研究所 [26]
过程工程研究所 [3]
合肥物质科学研究院 [3]
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期刊论文 [38]
发表日期
2021 [38]
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Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:
Xue, Haitao
;
Guo, Shuang
;
Hu, Tianwen
;
Wei, Daibao
;
Xie, Yuanchao
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  |  
浏览/下载:40/0
  |  
提交时间:2022/01/18
2 '-deoxy carbocyclic nucleoside
antiviral activity
hepatitis B virus
Mitsunobu reaction
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
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  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021
作者:
Yin, Yan-ping
;
Ma, Li-ying
;
Cao, Guo-zhen
;
Hua, Jing-han
;
Lv, Xiao-tong
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  |  
浏览/下载:78/0
  |  
提交时间:2022/01/10
small cell lung cancer
topotecan
DNA damage response
FK228
SLFN11
methylation
epigenetic modulation
Lactobacillus casei JY300-8 generated by (12)C6+beams mutagenesis inhibits tumor progression by modulating the gut microbiota in mice
期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2021, 卷号: 87, 页码: 14
作者:
Xu, Fuqiang
;
Li, Qiaoqiao
;
Wang, Shuyang
;
Bai, Jin
;
Dong, Miaoyin
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/12/08
Probiotic
Functional foods
Lactobacillus casei
Heavy ion beams induced-mutagenesis
Microbiota
Colon cancer
New synthetic adriamycin-incorporated chitosan nanoparticles with enhanced antioxidant, antitumor activities and pH-sensitive drug release
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 273, 页码: 11
作者:
Mi, Yingqi
;
Chen, Yuan
;
Gu, Guodong
;
Miao, Qin
;
Tan, Wenqiang
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  |  
浏览/下载:18/0
  |  
提交时间:2022/06/16
Chitosan
Drug release
Cell viability
Antitumor activity
Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635
作者:
Wu, Aihua
;
Chen, Yingzhi
;
Wang, Hairui
;
Chang, Ya
;
Zhang, Meng
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  |  
浏览/下载:27/0
  |  
提交时间:2022/01/18
Trichosanthin
Legumain
TRP2
Transcutaneous immunization
Adjuvant
Cancer vaccine
Protein engineering
Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2021, 页码: 14
作者:
Duan, Nianxiu
;
Li, Junjun
;
Song, Sha
;
Wang, Feng
;
Yang, Yiwei
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  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
drug delivery
pancreatic cancer
prodrugs
smart liposomes
tumor-specific vascular promotion
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
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  |  
浏览/下载:47/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Detachable Liposomes Combined Immunochemotherapy for Enhanced Triple-Negative Breast Cancer Treatment through Reprogramming of Tumor-Associated Macrophages
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 14, 页码: 6031-6041
作者:
Chen, Mingshu
;
Miao, Yunqiu
;
Qian, Kun
;
Zhou, Xin
;
Guo, Linmiao
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  |  
浏览/下载:28/0
  |  
提交时间:2021/11/04
Immunochemotherapy
triple-negative breast cancer
liposomes
tumor-associated macrophages
MMP2 response
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