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浏览/检索结果: 共16条，第1-10条 帮助 限定条件 发表日期：2021    专题：合肥物质科学研究院    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 An overview of kinase downregulators and recent advances in discovery approaches 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6 作者:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing 收藏  |  浏览/下载：39/0  |  提交时间：2022/01/25 CD71-Specific Aptamer Conjugated with Monomethyl Auristatin E for the Treatment of Uveal Melanoma 期刊论文 ACS APPLIED MATERIALS & INTERFACES, 2021 作者:  Zhang, Hui;  Jin, Cheng;  Zhang, Lin;  Peng, Bo;  Zhang, Yibin 收藏  |  浏览/下载：46/0  |  提交时间：2022/02/14 uveal melanoma  CD71  aptamer-drug conjugate  targeted drug delivery  tumor-targeted therapy   Protein degradation technology: a strategic paradigm shift in drug discovery 期刊论文 JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 卷号: 14 作者:  Li, Haobin;  Dong, Jinyun;  Cai, Maohua;  Xu, Zhiyuan;  Cheng, Xiang-Dong 收藏  |  浏览/下载：32/0  |  提交时间：2021/11/01 Protein degradation  Degradation pathway  Degradation technology  PROTAC  Monomeric degraders   A nanoselenium-coating biomimetic cytomembrane nanoplatform for mitochondrial targeted chemotherapy- and chemodynamic therapy through manganese and doxorubicin codelivery 期刊论文 JOURNAL OF NANOBIOTECHNOLOGY, 2021, 卷号: 19 作者:  Xiao, Jianmin;  Yan, Miao;  Zhou, Ke;  Chen, Hui;  Xu, Zhaowei 收藏  |  浏览/下载：49/0  |  提交时间：2021/08/30 Cell membrane  Reactive oxygen species  Superoxide dismutase-1  Glutathione peroxidase 4  Dual-mode therapeutic pathways  Drug delivery system   Recent Update on Development of Small-Molecule STAT3 Inhibitors for Cancer Therapy: From Phosphorylation Inhibition to Protein Degradation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64 作者:  Dong, Jinyun;  Cheng, Xiang-Dong;  Zhang, Wei-Dong;  Qin, Jiang-Jiang 收藏  |  浏览/下载：14/0  |  提交时间：2021/08/31 Nanocrystal-loaded liposome for targeted delivery of poorly water-soluble antitumor drugs with high drug loading and stability towards efficient cancer therapy 期刊论文 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 599 作者:  Liang, Huamin;  Zou, Fengming;  Liu, Qingwang;  Wang, Beilei;  Fu, Liyi 收藏  |  浏览/下载：68/0  |  提交时间：2021/05/17 Liposome  Drug nanocrystal  Core-shell  Drug delivery  Tumor therapy  BCR-ABL   Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118 作者:  Zhou, Xiaoting;  Gao, Yan;  Wang, Weiwei;  Yang, Xiaolin;  Yang, Xiuna 收藏  |  浏览/下载：53/0  |  提交时间：2021/06/15 succinate dehydrogenase  Mycobacterium smegmatis  electron transport chain  cryoelectron microscopy   Programmable Repurposing of Existing Drugs as Pharmaceutical Elements for the Construction of Aptamer-Drug Conjugates 期刊论文 ACS APPLIED MATERIALS & INTERFACES, 2021, 卷号: 13 作者:  Gao, Fei;  Zhou, Jinming;  Sun, Yang;  Yang, Cai;  Zhang, Shiyan 收藏  |  浏览/下载：49/0  |  提交时间：2021/04/26 aptamer  pharmaceutical elements  solid-phase synthesis  targeted therapy  drug delivery   In situ pepsin-assisted needle assembly of magnetic-graphitic-nanocapsules for enhanced gastric retention and mucus penetration 期刊论文 NANO TODAY, 2021, 卷号: 36 作者:  Cai, Xinqi;  Xu, Yiting;  Zhao, Lina;  Xu, Jiamei;  Li, Shengkai 收藏  |  浏览/下载：67/0  |  提交时间：2021/05/31 Harsh gastric environment  Pepsin-assisted assembly  Magnetic-graphitic-nanocapsule needle  Gastric retention  Mucus penetration   Thymoquinone Prevents Dopaminergic Neurodegeneration by Attenuating Oxidative Stress Via the Nrf2/ARE Pathway 期刊论文 FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 11 作者:  Dong, Jianjian;  Zhang, Xiaoming;  Wang, Shijing;  Xu, Chenchen;  Gao, Manli 收藏  |  浏览/下载：127/0  |  提交时间：2021/03/15 Parkinson's disease  thymoquinone  Nrf2/ARE signaling pathway  oxidative stress  neurodegeneration