QQ客服 官方微博 反馈留言

浏览/检索结果: 共17条，第1-10条 帮助 限定条件 发表日期：2021    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17 作者:  Li, Xinzhi;  Yuan, Bingchuan;  Lu, Min;  Wang, Yuqin;  Ding, Na 收藏  |  浏览/下载：37/0  |  提交时间：2022/01/18 GADD45 beta stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation 期刊论文 PHARMACOLOGICAL RESEARCH, 2021, 卷号: 173, 页码: 11 作者:  Dong, Yunxia;  Ma, Ningning;  Fan, Lei;  Yuan, Luyang;  Wu, Qian 收藏  |  浏览/下载：58/0  |  提交时间：2021/12/16 Non-alcoholic fatty liver disease  GADD45 beta  HSP72  Lipid accumulation  Insulin resistance   5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing 收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery 期刊论文 AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922 作者:  Tang, Ying;  Liu, Jinchang;  Wang, Yu;  Yang, Li;  Han, Bing 收藏  |  浏览/下载：44/0  |  提交时间：2022/01/04 Autophagy  functional recovery  ischemic stroke  lysophosphatidic acid receptor 5  microglial activation  poly (ADP-ribose) polymerase 14   Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219 作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu 收藏  |  浏览/下载：39/0  |  提交时间：2021/12/01 Hippo pathway  TEAD3  Covalent inhibitor  Palmitoylation inhibitor   Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310 作者:  Cheng, Jin-Tao;  Wang, Han-Min;  Yu, Jia-Hui;  Sun, Chen-Fan;  Cao, Fei 收藏  |  浏览/下载：28/0  |  提交时间：2021/12/01 fungus  Calcarisporium arbuscula  natural product  gene cluster activation  liver fibrosis   Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function 期刊论文 CELL RESEARCH, 2021, 页码: 18 作者:  Xu, Xiang;  Ding, Guangjin;  Liu, Caizhi;  Ding, Yuhan;  Chen, Xiaoxin 收藏  |  浏览/下载：63/0  |  提交时间：2021/11/04 Design and Synthesis of Alkyl Phenols Inhibitors of Death Associated Apoptotic Protein Kinase 2 (DRAK2) 期刊论文 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3204-3213 作者:  Zheng Zhang;  Dai Chengqiu;  Wu Honghong;  Li Jingya;  Nan Fajun 收藏  |  浏览/下载：19/0  |  提交时间：2021/11/04 death associated apoptotic protein kinase 2  diabetes  alkylphenols  inhibitors   miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes 期刊论文 LIFE SCIENCES, 2021, 卷号: 276, 页码: 13 作者:  Tai, Yusi;  Pu, Mei;  Yuan, Luyang;  Guo, Huijie;  Qiao, Junwen 收藏  |  浏览/下载：49/0  |  提交时间：2021/08/17 Mitophagy  PINK1  miR-34a-5p  CDS  Non-seed region   Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition 期刊论文 CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936 作者:  Gao, Jing;  Zhang, Hanwu;  Zhou, Fengqi;  Hou, Bo;  Chen, Meiwan 收藏  |  浏览/下载：17/0  |  提交时间：2021/08/17 Cancer immunotherapy  siRNA delivery  Acid-activatible micelleplex  CDK4  6 inhibitor  PD-L1 knockdown