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浏览/检索结果: 共67条，第1-10条 帮助 限定条件 发表日期：2021    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A simple and effective method for identification of Fraxini Cortex from different sources by multi-mode fingerprint combined with chemometrics 期刊论文 JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 16 作者:  Long, Huali;  Yao, Shuai;  Tian, Wenshuai;  Hou, Jinjun;  Lei, Min 收藏  |  浏览/下载：27/0  |  提交时间：2022/01/18 chemometrics  Fraxini Cortex  high-performance thin-layer chromatography  multi-mode fingerprint  ultra-high-performance liquid chromatography   Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo 收藏  |  浏览/下载：42/0  |  提交时间：2022/01/18 DPP4  distal mutation  enzymatic activity  molecular dynamics simulation  structure-function mechanism   Impurity Identification and Scale-Up of a Novel Glycopeptide Antibiotic 期刊论文 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2390-2402 作者:  Jiao, Shang;  Guan, Dongliang;  Xu, Lili;  Liu, Bo;  Shi, Weiwei 收藏  |  浏览/下载：19/0  |  提交时间：2022/01/18 glycopeptide antibiotics  impurity  analytical method  process optimization and development   Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文 JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251 作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen 收藏  |  浏览/下载：88/0  |  提交时间：2021/11/04 PDE4  Arctigenin  Psoriasis  Inflammation   A simultaneous identification and quantification strategy for determination of sulfhydryl-containing metabolites in normal- and high-fat diet hamsters using stable isotope labeling combined with LC-MS 期刊论文 ANALYTICA CHIMICA ACTA, 2021, 卷号: 1184, 页码: 13 作者:  Chang, Lu;  Lin, Feifei;  Cheng, Kai;  Li, Jiaomeng;  Sun, Xiaochu 收藏  |  浏览/下载：60/0  |  提交时间：2022/01/18 Sulfhydryl-containing metabolites  Stable isotope labeling  Identification  Quantification  Hyperlipidemia  Oxidative stress   Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy 期刊论文 STEM CELL RESEARCH & THERAPY, 2021, 卷号: 12, 期号: 1, 页码: 12 作者:  Ma, Chen;  Zhang, Ludi;  He, Ting;  Cao, Huiying;  Ren, Xiongzhao 收藏  |  浏览/下载：60/0  |  提交时间：2021/12/01 Raman spectroscopy  Cell therapy  Identification  Proliferating human hepatocytes  Dedifferentiation   Drug target inference by mining transcriptional data using a novel graph convolutional network framework 期刊论文 PROTEIN & CELL, 2021, 页码: 21 作者:  Zhong, Feisheng;  Wu, Xiaolong;  Yang, Ruirui;  Li, Xutong;  Wang, Dingyan 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/01 drug target inference  transcriptomics  deep learning  experimental verification   Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663 作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong 收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16 Generative Models for De Novo Drug Design 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14011-14027 作者:  Tong, Xiaochu;  Liu, Xiaohong;  Tan, Xiaoqin;  Li, Xutong;  Jiang, Jiaxin 收藏  |  浏览/下载：20/0  |  提交时间：2021/12/16 A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文 MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+ 作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng 收藏  |  浏览/下载：27/0  |  提交时间：2021/12/01