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科研机构
上海药物研究所 [36]
内容类型
期刊论文 [36]
发表日期
2020 [36]
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共36条,第1-10条
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发表日期:2020
内容类型:期刊论文
专题:上海药物研究所
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Phytochemicals from the Leaves of Cyclocarya paliurus and their 11 beta-HSD1 Enzyme Inhibitory Effects
期刊论文
CHEMISTRY & BIODIVERSITY, 2020, 页码: 7
作者:
Yan, Huan
;
Li, Xiang
;
Ni, Wei
;
Zhao, Qing
;
Leng, Ying
收藏
  |  
浏览/下载:118/0
  |  
提交时间:2021/05/24
Cyclocarya paliurus
dammarane-type triterpenoid saponins
11β
-HSD1 enzyme
inhibitory activity
Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15399-15409
作者:
Chen, Lin-Hai
;
Zhang, Qing
;
Xie, Xin
;
Nan, Fa-Jun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/05/24
Meroterpenoids with diverse structures and anti-inflammatory activities from Rhododendron anthopogonoides
期刊论文
PHYTOCHEMISTRY, 2020, 卷号: 180, 页码: 11
作者:
Shi, Qing
;
Li, Teng-Teng
;
Wu, Yong-Mei
;
Sun, Xin-Yu
;
Lei, Chun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/24
Rhododendron anthopogonoides Maxim
Ericaceae
Meroterpenoids
Anthoponoids A-I
Daurichromene D
Anti-inflammation
Direct quantification of anorethidrani disuccinate and determination of sterol metabolites by chemical derivatization combined with LC-MS/MS: Application to a Phase I pharmacokinetic study in humans
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1157, 页码: 9
作者:
Jiang, Jinfang
;
Li, Liang
;
Lu, Youming
;
Chen, Yunhui
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/24
Anorethidrani disuccinate
ACP
Sterol metabolite
Glycidyl trimethyl ammonium chloride
LC-MS/MS
The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-beta 1/NDRG2/MAPK Axis
期刊论文
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 11
作者:
Huang, Hui
;
Wang, Kuifeng
;
Liu, Qian
;
Ji, Feihong
;
Zhou, Hu
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/24
HSC
TGF-β
1
liver fibrosis
quantitative proteomics
NDRG2
Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408
作者:
Liu, Jian-Guo
;
Zhao, Danfeng
;
Gong, Qi
;
Bao, Fengxia
;
Chen, Wen-Wen
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
Glycogen synthase kinase-3
bisindole-substituted aminopyrazoles
Alzheimer's disease
oxidative neurotoxicity
microglial inflammation
Pulmonary Targeting Crosslinked Cyclodextrin Metal-Organic Frameworks for Lung Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 13
作者:
He, Yaping
;
Xiong, Ting
;
He, Siyu
;
Sun, Hongyu
;
Huang, Chenxi
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/12/21
cancer therapy
cyclodextrin frameworks
low-molecular-weight heparin
lung-targeting carriers
RGD peptide
Selective and sensitive fluorescence imaging reveals microenvironment-dependent behavior of NO modulators in the endothelial system
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 5, 页码: 466-472
作者:
Dong, Ying
;
Li, Xiao-Rong
;
Li, Jia
;
Zang, Yi
;
Li, Xin
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2020/12/21
Nitric oxide modulator
Drug screen
Fluorescence imaging
Microenvironment
Endothelial cell
Bisindole alkaloids with nitric oxide inhibitory activities from an alcohol extract of the Isatis indigotica roots
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 5
作者:
Zhang, Dongdong
;
Sun, Yu
;
Chen, Zhaoqiang
;
Jia, Qi
;
Zhu, Weiliang
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
Isatis indigotica
Bisindole alkaloids
Nitric oxide production
Isatisindigoticanines J and K
Isatindigosides H-J
Three new indole alkaloid glycosides with unusual structural features from the roots of Isatis indigotica
期刊论文
PHYTOCHEMISTRY LETTERS, 2020, 卷号: 39, 页码: 168-172
作者:
Zhang, Dongdong
;
Sun, Yu
;
Ruan, Deqing
;
Li, Jingyi
;
Chen, Kaixian
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
Isatis indigotica root
Indole alkaloid glycosides
Anti-inflammatory activity
Isatindigosides K and L
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