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山东大学 [3]
上海药物研究所 [2]
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期刊论文 [13]
发表日期
2019 [13]
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Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 21
作者:
Chen, Deheng
;
Lu, Tian
;
Yan, Ziqin
;
Lu, Wenchao
;
Lyu, Xilin
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浏览/下载:30/0
  |  
提交时间:2020/07/01
Bromodomain
BET protein
BD2
Selective
Crystal structure
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity
期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:
Zhu, Kongkai
;
Shao, Jingwei
;
Tao, Hongrui
;
Yan, Xue
;
Luo, Cheng
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  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
PRMT5 inhibitor
Anti-proliferative
Cellular target validation
Design and synthesis
Synthesis and structure-activity relationship studies of water-soluble beta-cyclodextrin-glycyrrhetinic acid conjugates as potential anti-influenza virus agents
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 328-338
作者:
Liang, Shuobin
;
Li, Man
;
Yu, Xiaojuan
;
Jin, Hongwei
;
Zhang, Yongmin
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  |  
浏览/下载:87/0
  |  
提交时间:2019/04/15
Glycyrrhetinic acid
Cyclodextrin
Click reaction
Influenza virus
Inhibitors
Synthesis and discovery of asiatic acid based 1,2,3-triazole derivatives as antitumor agents blocking NF-kappa B activation and cell migration
期刊论文
MEDCHEMCOMM, 2019, 卷号: 10, 期号: 4
作者:
Huang, Ri-Zhen
;
Liang, Gui-Bin
;
Li, Mei-Shan
;
Fang, Yi-Lin
;
Zhao, Shi-Feng
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  |  
浏览/下载:38/0
  |  
提交时间:2019/11/26
Design, synthesis, and antifungal activity of carboxamide derivatives possessing 1,2,3-triazole as potential succinate dehydrogenase inhibitors
期刊论文
Pesticide Biochemistry and Physiology, 2019
作者:
Wei Yan
;
Xing Wang
;
Ke Li
;
Tian-Xi Li
;
Jia-Jie Wang
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/13
1,2,3-triazole
Succinate dehydrogenase inhibitors
Fungicidal activity
Molecular docking simulation
Leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry. Part II
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 6, 页码: 978-990
作者:
Cao, Jiangying
;
Zang, Jie
;
Kong, Xiujie
;
Zhao, Chunlong
;
Chen, Ting
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
Aminopeptidase N
CD13
Anti-angiogenesis
Anti-metastasis
Triazole
Design, synthesis and antibacterial evaluation of novel 15-membered 11a-azahomoclarithromycin derivatives with the 1, 2, 3-triazole side chain
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 321-339
作者:
Qin, Yinhui
;
Teng, Yuetai
;
Ma, Ruixin
;
Bi, Fangchao
;
Liu, Zhiyang
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  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
Macrolide antibiotics
Antibacterial activity
Resistant bacterial
strains
Structure-activity relationships
Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors
期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 50, 页码: 28961-28986
作者:
Jiang, Xiangyi
;
Wu, Gaochan
;
Zalloum, Waleed A.
;
Meuser, Megan E.
;
Dick, Alexej
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  |  
浏览/下载:13/0
  |  
提交时间:2019/12/11
Synthesis of Novel 1,2,4-Triazole-3-thione Derivatives as Influenza Neuraminidase Inhibitors
期刊论文
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 卷号: Vol.56 No.8, 页码: 2192-2201
作者:
Liu, L
;
Ye, J
;
Xiao, MW
;
Yuan, KY
;
He, M
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  |  
浏览/下载:6/0
  |  
提交时间:2019/12/17
Antibacterial activity study of 1,2,4-triazole derivatives
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173
作者:
Gao, Feng
;
Wang, Tengfei
;
Xiao, Jiaqi
;
Huang, Gang
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/06
1,2,4-triazole
Hybrid compounds
Antibacterial activity
Structure-activity relationship
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