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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Deciphering molecular mechanism behind conformational change of the Sao Paolo metallo-beta-lactamase 1 by using enhanced sampling 期刊论文 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2019, 页码: 12 作者:  Chen, Jianzhong;  Wang, Jinan;  Pang, Laixue;  Wang, Wei;  Zhao, Juan 收藏  |  浏览/下载：47/0  |  提交时间：2020/07/01 Sao paolo metallo-beta-lactamase-1  REMD simulations  normal mode analysis  principal component analysis  drug resistance of antibiotics   Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity 期刊论文 ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 24, 页码: 15577-15584 作者:  Ding, Chunyong;  Wang, Fengyang;  Dang, Yijing;  Xu, Zhiai;  Li, Lingling 收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer 期刊论文 PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11 作者:  Wang Yuwei;  Tang Chunping;  Yao Sheng;  Lai Huanling;  Li Runze 收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 Non-small cell lung cancer  Natural product  Croton tiglium  Protein kinase C  Molecular modelling   Discovery of dihydrooxazolo[2,3-a]isoquinoliniums as highly specific inhibitors of hCE2 期刊论文 RSC ADVANCES, 2019, 卷号: 9, 期号: 61, 页码: 35904-35912 作者:  Ding, Lixia;  Wang, Lu;  Zou, Kun;  Li, Bo;  Song, Yunqing 收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01 Targeted photoswitchable imaging of intracellular glutathione by a photochromic glycosheet sensor 期刊论文 BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 15, 页码: 2380-2389 作者:  Chai, Xianzhi;  Han, Hai-Hao;  Zang, Yi;  Li, Jia;  He, Xiao-Peng 收藏  |  浏览/下载：68/0  |  提交时间：2020/07/01 intracellular GSH  molecular switches  photochromic glycosheet  photoswitchable imaging  2D MnO2 nanosheets   Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 10, 页码: 4303-4318 作者:  Chen, Jianzhong;  Wang, Jinan;  Yin, Baohua;  Pang, Laixue;  Wang, Wei 收藏  |  浏览/下载：114/0  |  提交时间：2020/07/01 beta-amyloid cleaving enzyme  binding selectivity  MSMD  hierarchical clustering analysis  MM-GBSA   Sensors, Imaging Agents, and Theranostics to Help Understand and Treat Reactive Oxygen Species Related Diseases 期刊论文 SMALL METHODS, 2019, 卷号: 3, 期号: 7, 页码: 42 作者:  Yon, Kai-Cheng;  Sedgwick, Adam C.;  Zang, Yi;  Chen, Guo-Rong;  He, Xiao-Peng 收藏  |  浏览/下载：66/0  |  提交时间：2020/07/01 fluorescence  imaging agents  ROS  sensors  theranostics   A Small-Molecule Compound Selectively Activates K2P Channel TASK-3 by Acting at Two Distant Clusters of Residues 期刊论文 MOLECULAR PHARMACOLOGY, 2019, 卷号: 96, 期号: 1, 页码: 26-35 作者:  Tian, Fuyun;  Qiu, Yunguang;  Lan, Xi;  Li, Min;  Yang, Huaiyu 收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid Channel 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 3, 页码: 1373-1384 作者:  Chai, Hao;  Cheng, Xi;  Zhou, Bin;  Zhao, Lifen;  Lin, Xianhua 收藏  |  浏览/下载：36/0  |  提交时间：2020/07/01