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上海药物研究所 [29]
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期刊论文 [306]
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Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data
期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 16
作者:
Zhang, Lirong
;
Xue, Gaogao
;
Liu, Junjie
;
Li, Qianzhong
;
Wang, Yong
收藏
  |  
浏览/下载:223/0
  |  
提交时间:2019/01/11
Transcription factor
Histone modification
Co-localization
Dynamics
Design, synthesis, and bioactivity evaluation of novel Bcl-2/HDAC dual-target inhibitors for the treatment of multiple myeloma
期刊论文
Bioorganic & medicinal chemistry letters, 2018
作者:
Zhou, Ruolan
;
Fang, Shaoyu
;
Zhang, Minmin
;
Zhang, Qingsen
;
Hu, Jian
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2019/01/08
Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812
作者:
Zheng, Qiangang
;
Chen, Ziqi
;
Wan, Huixin
;
Tang, Shuai
;
Ye, Yan
收藏
  |  
浏览/下载:235/0
  |  
提交时间:2019/01/08
IDH1 inhibitor
Imidazole cyclopropyl amine
Structure-based rational design
Antifungal Prenylated Diphenyl Ethers from Arthrinium arundinis, an Endophytic Fungus Isolated from the Leaves of Tobacco (Nicotiana tabacum L.)
期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 7
作者:
Zhang, Peng
;
Li, Xin
;
Yuan, Xiao-Long
;
Du, Yong-Mei
;
Wang, Bin-Gui
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  |  
浏览/下载:42/0
  |  
提交时间:2019/05/15
tobacco-derived endophytic fungus
Arthrinium arundinis
Nicotiana tabacum L
prenylated diphenyl ethers
antifungal activity
cytotoxicity
Significance of the epidermal growth factor receptor mutation status and differences among molecular subgroups in surgically resected lung microinvasive adenocarcinoma
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 16, 期号: 6, 页码: 7057-7067
作者:
Li, Ming
;
Li, Chuanying
;
Ke, Li
;
Zhan, Mali
;
Cheng, Min
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  |  
浏览/下载:240/0
  |  
提交时间:2019/06/20
epidermal growth factor receptor
mutation
non-small cell lung cancer
microinvasive adenocarcinoma
molecular subgroup
A Biomimetic Human Gut-on-a-Chip for Modeling Drug Metabolism in Intestine
期刊论文
ARTIFICIAL ORGANS, 2018, 卷号: 42, 期号: 12, 页码: 1196-1205
作者:
Guo, Yaqiong
;
Li, Zhongyu
;
Su, Wentao
;
Wang, Li
;
Zhu, Yujuan
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  |  
浏览/下载:63/0
  |  
提交时间:2019/06/20
Gut-on-a-chip
Caco-2
Intestinal metabolism
Biomimetic
Drug metabolism
H2O2-induced acclimation of photosystem II to excess light is mediated by alternative respiratory pathway and salicylic acid
期刊论文
PHOTOSYNTHETICA, 2018, 卷号: 56, 页码: 1154-1160
作者:
Hou, Q. Z.
;
Wang, Y. P.
;
Liang, J. Y.
;
Jia, L. Y.
;
Feng, H. Q.
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  |  
浏览/下载:14/0
  |  
提交时间:2018/10/08
excess light
hydrogen peroxide
photosystem II
salicylic acid
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells
期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
作者:
Hu, Yu
;
Li, Xiao-Nian
;
Ma, Ze-Jin
;
Puno, Pema-Tenzin
;
Zhao, Yong
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  |  
浏览/下载:55/0
  |  
提交时间:2019/03/18
ent-kaurane-type diterpenoid derivatives
antitumor
synthesis
Eucalypglobulusals A-J, Formyl-Phloroglucinol-Terpene Meroterpenoids from Eucalyptus globulus Fruits
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 12, 页码: 2638-2646
作者:
Qin, Xu-Jie
;
Jin, Ling-Yu
;
Yu, Qian
;
Liu, Hui
;
Khan, Afsar
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/03/18
Expression of Human Cytomegalovirus IE1 Leads to Accumulation of Mono-SUMOylated PML That Is Protected from Degradation by Herpes Simplex Virus 1 ICP0
期刊论文
JOURNAL OF VIROLOGY, 2018, 卷号: 92, 期号: 23, 页码: 12
作者:
Tang, Qiyi
;
Luo, Min-Hua
;
Reeves, Inez
;
Ahn, Jin-Hyun
;
Wen, Fayuan
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  |  
浏览/下载:62/0
  |  
提交时间:2018/12/29
cytomegalovirus (CMV)
immediate-early protein 1 (IE1)
herpes simplex virus (HSV)
infected cellular protein (ICP0)
promyelocytic leukemia protein (PML)
nuclear domain 10 (ND10)
SUMOylation
HSV-1
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