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科研机构
上海药物研究所 [20]
江苏大学 [11]
山东大学 [10]
上海生物化学与细胞... [10]
武汉大学 [9]
水生生物研究所 [6]
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期刊论文 [136]
会议论文 [3]
发表日期
2018 [139]
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Biochemist... [1]
Cell Biolo... [1]
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发表日期:2018
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Identification of a cellularly active SIRT6 allosteric activator
期刊论文
NATURE CHEMICAL BIOLOGY, 2018, 卷号: 14, 期号: 12, 页码: 1118-+
作者:
Huang, Zhimin
;
Zhao, Junxing
;
Deng, Wei
;
Chen, Yingyi
;
Shang, Jialin
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2019/01/08
The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine
期刊论文
MOLECULAR GENETICS AND METABOLISM REPORTS, 2018, 卷号: 17, 页码: 46-52
作者:
Li, Hong
;
Zhao, Lihua
;
Singh, Rani
;
Ham, J. Nina
;
Fadoju, Doris O.
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  |  
浏览/下载:84/0
  |  
提交时间:2019/01/08
Glucagon receptor
Newborn screening
GCGR mutation
Hyperaminoacidemia
Mahvash disease
Pancreatic alpha cell hyperplasia (ACH)
Pancreatic neuroendocrine tumor (PNET)
Jeotgalibacillus proteolyticus sp. nov., a protease-producing bacterium isolated from ocean sediments
期刊论文
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2018, 卷号: 68, 期号: 12, 页码: 3790-3795
作者:
Li, Yan
;
Zhang, Zhenpeng
;
Xu, Zhenxing
;
Fang, Dongbo
;
Wang, En Tao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/08
marine bacterium
ocean sediment
taxonomy
Jeotgalibacillus proteolyticus sp. nov.
Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors
期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 281-294
作者:
Xing, Jing
;
Zhang, Rukang
;
Jiang, Xiangrui
;
Hu, Tianwen
;
Wang, Xinjun
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  |  
浏览/下载:86/0
  |  
提交时间:2019/01/08
A novel transcription factor Rwdd1 and its SUMOylation inhibit the expression of sqr, a key gene of mitochondrial sulfide metabolism in Urechis unicinctus
期刊论文
AQUATIC TOXICOLOGY, 2018, 卷号: 204, 页码: 180-189
作者:
Li, Xueyu
;
Liu, Xiaolong
;
Qin, Zhenkui
;
Wei, Maokai
;
Hou, Xitan
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  |  
浏览/下载:57/0
  |  
提交时间:2019/06/20
Urechis unicinctus
Sulfide
Quinine oxidoreductase gene
RWO domain-containing 1
Transcription factor
Transcriptional regulation
SUMOylation
A novel transcription factor rwdd1 and its sumoylation inhibit the expression of sqr, a key gene of mitochondrial sulfide metabolism in urechis unicinctus
期刊论文
Aquatic toxicology, 2018, 卷号: 204, 页码: 180-189
作者:
Li, Xueyu
;
Liu, Xiaolong
;
Qin, Zhenkui
;
Wei, Maokai
;
Hou, Xitan
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/05/08
Urechis unicinctus
Sulfide
Quinine oxidoreductase gene
Rwo domain-containing 1
Transcription factor
Transcriptional regulation
Sumoylation
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407
作者:
Lu, Wenchao
;
Xiong, Huan
;
Chen, Yu
;
Wang, Chen
;
Zhang, Hao
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  |  
浏览/下载:138/0
  |  
提交时间:2019/01/08
Drug discovery
Epigenetics
Histone acetyltransferase
P300/CBP
Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Meng, Jian
;
Liu, Xiao-Yun
;
Ma, Sheng
;
Zhang, Hua
;
Yu, Song-da
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  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
An Efficient Approach for Selective Enrichment of Histone Modification Readers Using Self-Assembled Multivalent Photoaffinity Peptide Probes
期刊论文
ANALYTICAL CHEMISTRY, 2018, 卷号: 90, 期号: 19, 页码: 11385-11392
作者:
Zhang, Kai
;
Zhai, Guijin
;
Dong, Hanyang
;
Guo, Zhenchang
;
Feng, Wei
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  |  
浏览/下载:49/0
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提交时间:2019/06/20
Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 80, 页码: 649-654
作者:
Zhang, Li
;
Chen, Yantao
;
Liu, Na
;
Li, Linjuan
;
Xiao, Senhao
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Pyrimidylaminoquinoline
Nonnucleoside DOT1L inhibitors
Amino side chains
Mixed-linage leukemia
Histone lysine methyltransferase
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