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Design, synthesis, and bioactivity evaluation of novel Bcl-2/HDAC dual-target inhibitors for the treatment of multiple myeloma 期刊论文
Bioorganic & medicinal chemistry letters, 2018
作者:  Zhou, Ruolan;  Fang, Shaoyu;  Zhang, Minmin;  Zhang, Qingsen;  Hu, Jian
收藏  |  浏览/下载:97/0  |  提交时间:2019/01/08
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/11
Alterations of early-stage decomposition of leaves and absorptive roots by deposition of nitrogen and phosphorus have contrasting mechanisms 期刊论文
SOIL BIOLOGY & BIOCHEMISTRY, 2018, 卷号: 127, 页码: 213-222
作者:  Jiang, Lei;  Kou, Liang;  Li, Shenggong
收藏  |  浏览/下载:36/0  |  提交时间:2019/05/23
Modified citrus pectin inhibited bladder tumor growth through downregulation of galectin-3 期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1885-1893
作者:  Fang, Tian;  Liu, Dan-Dan;  Ning, He-Ming;  Sun, Jing-Ya;  Huang, Xiao-Jing
收藏  |  浏览/下载:71/0  |  提交时间:2019/01/08
VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via activation of AKT-dependent ROS production in NSCLC 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2018, 卷号: 129, 页码: 177-185
作者:  Zhou, Ling;  Yi, Yuetao;  Yuan, Qing;  Zhang, Jing;  Li, Youjie
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/08
Graphene quantum dots in alveolar macrophage: uptake-exocytosis, accumulation in nuclei, nuclear responses and DNA cleavage 期刊论文
PARTICLE AND FIBRE TOXICOLOGY, 2018, 卷号: 15, 页码: 45
作者:  Xu, Lina;  Dai, Yanhui;  Wang, Zhenyu;  Zhao, Jian;  Li, Fei
收藏  |  浏览/下载:197/0  |  提交时间:2020/07/08
Rapid re-evaluation of bioactive saponins from Paris polyphylla using affinity ultrafiltration-LC/MS with multiple drug targets 期刊论文
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2018, 卷号: 434, 页码: 87-92
作者:  Guo, Mingquan;  Chen, Guilin
收藏  |  浏览/下载:58/0  |  提交时间:2018/12/29
Oxidative stress and cytotoxicity induced by tetrachlorobisphenol A in Saccharomyces cerevisiae cells 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 161, 页码: 1-7
作者:  Li, Hao;  Ji, Zhihua;  Zhang, Yaxian;  Tian, Juan;  Wang, Fengbang
收藏  |  浏览/下载:25/0  |  提交时间:2019/06/20
STAT3 activation confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive breast cancer 期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 10, 页码: 3305-3315
作者:  Wang, Lei;  Wang, Quanren;  Gao, Mingzhao;  Fu, Li;  Li, Yun
收藏  |  浏览/下载:50/0  |  提交时间:2019/01/08
Phosphate affects adsorption and desorption of oxytetracycline in the seawater-sediment systems 期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2018, 卷号: 25, 期号: 28 SI, 页码: 28160-28168
作者:  Li, Jia;  Zhang, Hua;  Yuan, Guodong
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/08


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