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上海药物研究所 [15]
复旦大学上海医学院 [5]
中国医学科学院 北京... [5]
西安交通大学 [4]
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期刊论文 [69]
会议论文 [2]
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2018 [71]
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Human pharmacokinetics of ginkgo terpene lactones and impact of carboxylation in blood on their platelet-activating factor antagonistic activity
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1935-1946
作者:
Liu, Xin-Wei
;
Yang, Jun-Ling
;
Niu, Wei
;
Jia, Wei-Wei
;
Olaleye, Olajide E
收藏
  |  
浏览/下载:105/0
  |  
提交时间:2019/01/08
18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-Yan
;
Cui, Shi-Chao
;
Wang, Le
;
Zhang, Yi-Ting
;
Yan, Xiao-Xia
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2019/01/08
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-yan
;
Cui, Shi-chao
;
Wang, Le
;
Zhang, Yi-ying
;
Yan, Xiao-xia
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
hepatoprotective effect
cholestatic liver injury
18 beta-glycyrrhetinic acid (18b-GA)
FXR
Sirt1
bile acid transporters
In vivo theranostics with near-infrared-emitting carbon dots-highly efficient photothermal therapy based on passive targeting after intravenous administration
期刊论文
LIGHT-SCIENCE & APPLICATIONS, 2018, 卷号: 7, 页码: 11
作者:
Qu, Songnan
;
Zboril, Radek
;
Liu, Chengbo
;
Song, Liang
;
Wu, Changfeng
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/08/21
Preliminary test on the distribution, hydrolyzation and excretion of aluminum dialkyl phosphinate flame retardants in rats
期刊论文
ENVIRONMENTAL POLLUTION, 2018, 卷号: 242, 页码: 1998-2004
作者:
Li, Lisha
;
Liu, Yuchen
;
Liu, Jiyan
;
Liu, Jingfu
;
Niu, Yumin
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/06/20
Aluminum methylcyclohexyl phosphinic
Distribution
Excretion
Hydrolysis
Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Meng, Jian
;
Liu, Xiao-Yun
;
Ma, Sheng
;
Zhang, Hua
;
Yu, Song-da
收藏
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浏览/下载:98/0
  |  
提交时间:2019/01/08
Artificial intelligence in drug design
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2018, 卷号: 61, 期号: 10, 页码: 1191-1204
作者:
Zhong, Feisheng
;
Xing, Jing
;
Li, Xutong
;
Liu, Xiaohong
;
Fu, Zunyun
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
drug design
artificial intelligence
deep learning
QSAR
ADME/T
Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
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  |  
浏览/下载:101/0
  |  
提交时间:2019/01/08
Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate
期刊论文
DRUG METABOLISM AND DISPOSITION, 2018, 卷号: 46, 期号: 9, 页码: 1320-1328
作者:
Hou, Xiangyu
;
Zhou, Jialan
;
Yu, Songda
;
Zhou, Lei
;
Zhang, Yifan
收藏
  |  
浏览/下载:70/0
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提交时间:2019/01/08
Discovery of thiophene-containing biaryl amide derivatives as novel glucagon receptor antagonists
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 92, 期号: 1, 页码: 1241-1254
作者:
Li, Jia
;
Feng, Yang
;
Li, Huihui
;
Shu, Shuangjie
;
Dai, Antao
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
biaryl amide
glucagon receptor antagonist
molecular simulation
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