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上海药物研究所 [99]
山东大学 [31]
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湖南大学 [25]
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期刊论文 [626]
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2018 [639]
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浏览/检索结果:
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Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data
期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 16
作者:
Zhang, Lirong
;
Xue, Gaogao
;
Liu, Junjie
;
Li, Qianzhong
;
Wang, Yong
收藏
  |  
浏览/下载:223/0
  |  
提交时间:2019/01/11
Transcription factor
Histone modification
Co-localization
Dynamics
Effect of patchouli alcohol on Helicobacter pylori-induced neutrophil recruitment and activation
期刊论文
International immunopharmacology, 2018, 卷号: 68, 页码: 7-16
作者:
Ren, Wen-Kang
;
Xu, Yi-Fei
;
Wei, Wen-Hui
;
Huang, Ping
;
Lian, Da-Wei
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2019/01/08
Design, synthesis, and bioactivity evaluation of novel Bcl-2/HDAC dual-target inhibitors for the treatment of multiple myeloma
期刊论文
Bioorganic & medicinal chemistry letters, 2018
作者:
Zhou, Ruolan
;
Fang, Shaoyu
;
Zhang, Minmin
;
Zhang, Qingsen
;
Hu, Jian
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2019/01/08
Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4(+) T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4
期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9, 页码: 15
作者:
Hu, Qinxue
;
Gong, Sitang
;
Liu, Yalan
;
Li, Mei
;
Hu, Kai
收藏
  |  
浏览/下载:125/0
  |  
提交时间:2019/03/05
HSV-2
CXCR3 ligands
CD4(+) T cells
recruitment
ICP4
Genetically-engineered protein prodrug-like nanoconjugates for tumor-targeting biomimetic delivery via a SHEATH strategy
期刊论文
Nanoscale, 2018
作者:
Chang, Ya
;
Yao, Shuo
;
Chen, Yifang
;
Huang, Jingjing
;
Wu, Aihua
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  |  
浏览/下载:75/0
  |  
提交时间:2019/01/08
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Solution structure of TbCentrin4 from Trypanosoma brucei and its interactions with Ca2+ and other centrins
期刊论文
BIOCHEMICAL JOURNAL, 2018, 卷号: 475, 页码: 3763-3778
作者:
Shan, Fangzhen
;
Ye, Kaiqin
;
Zhang, Jiahai
;
Liao, Shanhui
;
Zhang, Xuecheng
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2019/12/25
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction
期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 597-609
作者:
Chen, Danqi
;
Chen, Yuehong
;
Lian, Fulin
;
Chen, Liu
;
Li, Yanlian
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  |  
浏览/下载:90/0
  |  
提交时间:2019/01/08
Effect of Pore Structure on Protein Capacity in Macroporous Polymer Chromatographic Supports
期刊论文
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2018, 卷号: 39, 期号: 12, 页码: 2673-2678
作者:
Li Heng
;
Wang Shaoyun
;
Fang Jiaxuan
;
Zhao Lan
;
Jin Haibo
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/04/03
Macroporous Polymer Microsphere
Chromatographic Media
Protein Capactiy
High Through-put
Self-assembly of antigen proteins into nanowires greatly enhances the binding affinity for high-efficiency target capture
期刊论文
Acs applied materials & interfaces, 2018, 卷号: 10, 期号: 48, 页码: 41019-41025
作者:
Men, Dong
;
Zhou, Juan
;
Li, Wei
;
Wei, Cui-Hua
;
Chen, Yuan-Yuan
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  |  
浏览/下载:73/0
  |  
提交时间:2019/05/08
Self-assembly
Protein nanowire
Polyvalent interaction
Binding affinity
Sensitive immunoassay
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