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科研机构
湖南中医药大学 [6]
内容类型
期刊论文 [6]
发表日期
2018 [6]
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发表日期:2018
专题:湖南中医药大学
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Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular Immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
Prion-like propagation of α-synuclein in the gut-brain axis
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 341-346
作者:
Chen, Ying
;
Shao, Qianhang
;
Yuan, Yu-He*
;
Chen, Nai-Hong*
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/27
CNS
central nervous system
DA
dopamine
DMV
dorsal motor nucleus of the vagus
ENS
enteric nervous system
GI
gastrointestinal
IL-1
interleukin-1
LBs
Lewy bodies
LPS
lipopolysaccharide
LAG3
lymphocyte-activation gene 3
MPTP
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
P301L
mutant Tau
PD
Parkinson's disease
PNS
peripheral nervous system
ROS
reactive oxygen species
SCFA
short chain fatty acids
SN
substantia nigra
TH
Tyrosine hydroxylase
TLR 2
Toll-like receptor 2
TNTs
tunneling nanotubes
α-synuclein
Prion-like
Enteric nervous system
Gut-brain axis
Non-motor symptom
Parkinson’s disease
Systemic or Forebrain Neuron-Specific Deficiency of Geranylgeranyltransferase-1 Impairs Synaptic Plasticity and Reduces Dendritic Spine Density
期刊论文
Neuroscience, 2018, 卷号: 373, 页码: 207-217
作者:
Hottman, David
;
Cheng, Shaowu(成绍武)
;
Gram, Andrea
;
LeBlanc, Kyle
;
Yuan, Li-Lian
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/27
ALS
amyotrophic lateral sclerosis
aCSF
artificial cerebrospinal fluid
AD
Alzheimer’s disease
ANOVA
analysis of variance
AO
apical oblique
BS
basal shaft
CaMKII α
Ca2+/calmodulin-dependent protein kinase
CNS
central nervous system
Cre+
Cre recombinase transgene positive
fEPSPs
field excitatory post-synaptic potentials
FPP
farnesyl pyrophosphate
FT
farnesyltransferase
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
GGPP
geranylgeranyl pyrophosphate
GGT
geranylgeranyltransferase-1
GGT+/−
GGT-haplodeficient
GGTf/f
GGT gene floxed
GGTf/fCre+
conditional forebrain neuron-specific GGT knockout
GTP
guanosine triphosphate
I/O
input/output
LTP
long-term potentiation
PPF
paired-pulse facilitation
WT
wild type
protein prenylation
geranylgeranyltransferase
knockout mouse models
small GTPases
synaptic plasticity
dendritic spine density
Myelin injury in the central nervous system and Alzheimer's disease
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:
Wang, Sha-Sha
;
Zhang, Zhao
;
Zhu, Tian-Bi
;
Chu, Shi-Feng
;
He, Wen-Bin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/27
OLG
oligodendrocyte
CNS
central nervous system
SC
Schwann cell
PNS
peripheral nervous system
MBP
myelin basic protein
PLP
proteolipid protein
P0/MPZ
myelin protein zero
EAE
experimental allergic encephalomyelitis
MS
multiple sclerosis
CNP
2′ 3′-cyclic nucleotide 3′-phosphodiesterase
MAG
myelin associated glycoprotein
MOG
myelin oligodendrocyte glycoprotein
AD
Alzheimer's disease
OPC
oligodendrocyte precursor cell
NPC
neural progenitor cell
ROS
reactive oxygen species
TNF
tumour necrosis factor
AIF
apoptosis-inducing factor
IFN-γ
interferon gamma
ERK1/2
extracellular signal-regulated kinases-1 and -2
MAPK
mediators of mitogen-activated protein kinase
FGFR1/2
fibroblast growth factor receptors-1 and -2
Dock3
dedicator of cytokinesis 3
PERK
pancreatic endoplasmic reticulum kinase
GEF
guanine nucleotide exchange factor
SIRT2
sirtuin 2
NOD2
Nucleotide-binding oligomerization domain containing protein 2
RIPK2
receptor-interacting serine/threonine kinase 2
Shh
Sonic Hedgehog
NMO
neuromyelitis optica
ADEM
acute disseminated encephalomyelitis
ANHLE
acute necrotizing hemorrhagic leukoencephalitis
CPM
central pontine myelinolysis
Aβ
beta-amyloid
SP
senile plaque
NFT
neurofibrillary tangle
MRI
magnetic resonance imaging
Myelin
Oligodendrocyte
Demyelination
Neurodegenerative diseases
Alzheimer’s disease
Chemokines play complex roles in cerebral ischemia
期刊论文
Neurochemistry International, 2018, 卷号: 112, 页码: 146-158
作者:
Chen, Chen
;
Chu, Shi-Feng
;
Liu, Dan-Dan
;
Zhang, Zhao
;
Kong, Ling-Lei
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/12/27
Chemokine
Cerebral ischemia
Ischemic stroke
IS
ischemic stroke
NSCs
neural stem cell
NPCs
neural progenitor cells
BMSCs
bone marrow stromal cells
ELR
glutamic acid-leucine-arginine
MCP
monocytes chemoattractant protein
MCAo
middle cerebral artery occlusion
tMCAo
transient MCAo
CNS
central nervous system
MIP
macrophage inflammatory protein
BBB
blood brain barrier
HI
hypoxia ischemia
CSF
cerebrospinal fluid
CI
cerebral infarction
WT
wildtype
pMCAo
permanent MCAo
ET
endothelin
I/R
ischemia/reperfusion
SCID
Severe Combined Immunodeficiency
ENA-78
epithelial neutrophil-activating peptide-78
IL-8
interleukin 8
PMNL
polymorphonuclear leukocyte
MSCs
mesenchymal stem cells
VEGF
vascular endothelial growth factor
CINC
cytokine-induced neutrophil chemoattractant
IP-10
interferon-gamma inducible protein-10
NK
natural killer
SDF-1
stromal cell-derived factor-1
EPCs
endothelial progenitor cells
HSCs
hematopoietic stem cells
HUVECs
human umbilical vein endothelial cells
TIA
transient ischemic attack
OGD
oxygen glucose deprivation
GPCs
glial precursor cells
CMKLR1
chemerin-like receptor-1
AIS
acute ischemic stroke
CKLF1
chemokine-like factor 1
CBP
chemokine-binding protein
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
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