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科研机构
上海药物研究所 [11]
内容类型
期刊论文 [11]
发表日期
2017 [11]
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发表日期:2017
专题:上海药物研究所
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Hypoxia induces universal but differential drug resistance and impairs anticancer mechanisms of 5-fluorouracil in hepatoma cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1642-1654
作者:
Li, Jing-qiu
;
Wu, Xian
;
Gan, Lu
;
Yang, Xiang-liang
;
Miao, Ze-hong
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
hepatocellular carcinoma
hypoxia
5-fluorouracil
sorafenib
drug resistance
Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248
作者:
Chen, Jianzhong
;
Wang, Jinan
;
Zhu, Weiliang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Dual-Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug-Resistant Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 44
作者:
Zhao, Pengfei
;
Yin, Weimin
;
Wu, Aihua
;
Tang, Yisi
;
Wang, Jinyu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
albumin nanoparticles
combination therapy
mannose receptors
multidrug resistance
SPARC
The blueberry component pterostilbene has potent anti-myeloma activity in bortezomib-resistant cells
期刊论文
ONCOLOGY REPORTS, 2017, 卷号: 38, 期号: 1, 页码: 488-496
作者:
Chen, Gege
;
Xu, Zhijian
;
Chang, Gaomei
;
Hou, Jun
;
Hu, Liangning
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
pterostilbene
multiple myeloma
bortezomib-resistant cells
apoptosis
cell cycle
histone deacetylase inhibitors
Aberrant intracellular metabolism of T-DM1 confers T-DM1 resistance in human epidermal growth factor receptor 2-positive gastric cancer cells
期刊论文
CANCER SCIENCE, 2017, 卷号: 108, 期号: 7, 页码: 1458-1468
作者:
Wang, Hongbin
;
Wang, Wenqian
;
Xu, Yongping
;
Yang, Yong
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Antibody-drug conjugate
drug resistance
HER2
T-DM1
V-ATPase
Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 6, 页码: 885-896
作者:
Kang, Xue-jia
;
Wang, Hui-yuan
;
Peng, Hui-ge
;
Chen, Bin-fan
;
Zhang, Wen-yuan
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
human colon cancer
multidrug resistance
doxorubicin
dihydroartemisinin
combination therapy
tumor-targeted delivery
mannosylated liposome
mannose receptor
Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 卷号: 18, 期号: 5
作者:
Huang, Qi
;
Wang, Ting
;
Yang, Liu
;
Wang, He-Yao
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
ginsenoside Rb2
NAFLD
type 2 diabetes
hepatosteatosis
autophagy
AMPK
sirt1
Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance
期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 5, 页码: 1429-1438
作者:
Chen, Yingzhi
;
Zhang, Meng
;
Jin, Hongyue
;
Tang, Yisi
;
Wu, Aihua
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
multidrug resistance
trichosanthin
matrix metalloproteinase
paclitaxel
caspase 9 phosphorylation
intein-mediated protein ligation
PEGylation
Nimesulide and 4 '-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis
期刊论文
DRUG METABOLISM AND DISPOSITION, 2017, 卷号: 45, 期号: 5, 页码: 441-448
作者:
Zhou, Lei
;
Pang, Xiaoyan
;
Jiang, Jingfang
;
Zhong, Dafang
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 5003-5015
作者:
Song, Qiaoling
;
Sun, Xiaoxiao
;
Guo, Hui
;
Yu, Qiang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
receptor tyrosine kinases
AKT
colorectal cancer
drug combination
RAS/RAF
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