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浏览/检索结果: 共20条，第1-10条 帮助 限定条件 发表日期：2017    专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Highly Selective Activation of Heat Shock Protein 70 by Allosteric Regulation Provides an Insight into Efficient Neuroinflammation Inhibition 期刊论文 EBIOMEDICINE, 2017 Wang, Li-Chao; Liao, Li-Xi; Lv, Hai-Ning; Liu, Dan; Dong, Wei; Zhu, Jian; Chen, Jin-Feng; Shi, Meng-Ling; Fu, Ge; Song, Xiao-Min; Jiang, Yong; Zeng, Ke-Wu; Tu, Peng-Fei 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 Heat shock protein 70 (Hsp70)  Handelin  Drug target  Covalent modification  Neuroinflammation  HEAT-SHOCK PROTEINS  T-CELL REGULATION  HIGH-FAT DIET  KAPPA-B  AUTOIMMUNE ARTHRITIS  HSP70  STRESS  INFLAMMATION  EXPRESSION  POLYUBIQUITINATION   Piconewton-Scale Analysis of Ras-BRaf Signal Transduction with Single-Molecule Force Spectroscopy 期刊论文 SMALL, 2017 Lim, Chae-Seok; Wen, Cheng; Sheng, Yanghui; Wang, Guangfu; Zhou, Zhuan; Wang, Shiqiang; Zhang, Huaye; Ye, Anpei; Zhu, J. Julius 收藏  |  浏览/下载：9/0  |  提交时间：2017/12/03 AMPA RECEPTOR TRAFFICKING  CYSTEINE-RICH DOMAIN  SYNAPTIC PLASTICITY  OPTICAL TWEEZERS  ACTIVATION  MECHANISMS  INSERTION  KINASES  DISPLAY  BINDING   Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State 期刊论文 CELL STEM CELL, 2017 Li, Xiang; Liu, Defang; Ma, Yantao; Du, Xiaomin; Jing, Junzhan; Wang, Lipeng; Xie, Bingqing; Sun, Da; Sun, Shaoqiang; Jin, Xueqin; Zhang, Xu; Zhao, Ting; Guan, Jingyang; Yi, Zexuan; Lai, Weifeng; Zheng, Ping; Huang, Zhuo; Chang, Yanzhong; Chai, Zhen; Xu, Jun; Deng, Hongkui 收藏  |  浏览/下载：11/0  |  提交时间：2017/12/03 PLURIPOTENT STEM-CELLS  SMALL-MOLECULE COMPOUNDS  FUNCTIONAL-NEURONS  DIRECT CONVERSION  PURKINJE NEURONS  SOMATIC-CELLS  HUMAN ES  FUSION  HEPATOCYTES  DISEASE   Dynamic and modular gene regulatory networks drive the development of gametogenesis 期刊论文 BRIEFINGS IN BIOINFORMATICS, 2017 Che, Dongxue; Wang, Yang; Bai, Weiyang; Li, Leijie; Liu, Guiyou; Zhang, Liangcai; Zuo, Yongchun; Tao, Shiheng; Hua, Jinlian; Liao, Mingzhi 收藏  |  浏览/下载：8/0  |  提交时间：2017/12/03 gametogenesis  dynamics  modularity  protein-protein interaction network  Gametogenesis Molecule Online  GERM-CELL DIFFERENTIATION  SMALL NONCODING RNAS  CAENORHABDITIS-ELEGANS  BIOLOGICAL NETWORKS  PATHWAY  TEXT  SPERMATOGENESIS  SEQ  DATABASE  TARGETS   Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii 期刊论文 CELL RESEARCH, 2017 Li, Zhifei; Guo, Qiang; Zheng, Lvqin; Ji, Yongsheng; Xie, Yi-Ting; Lai, De-Hua; Lun, Zhao-Rong; Suo, Xun; Gao, Ning 收藏  |  浏览/下载：10/0  |  提交时间：2017/12/03 cryo-electron microscopy  ribosome  translation  Trichomonas vaginalis  Toxoplasma gondii  RNA  TRANSLATION INITIATION COMPLEX  PEPTIDYL-TRANSFERASE CENTER  NEIGHBOR-JOINING METHOD  N-TERMINAL EXTENSION  EUKARYOTIC RIBOSOME  MITOCHONDRIAL RIBOSOME  70S RIBOSOME  ANGSTROM RESOLUTION  ELECTRON-MICROSCOPY  PROTEIN-SYNTHESIS   Investigation of the interactions between methylene blue and intramolecular G-quadruplexes: an explicit distinction in electrochemical behavior 期刊论文 ANALYST, 2017 Cao, Ting; Zhang, Fang-Ting; Cai, Liang-Yuan; Zhou, Ying-Lin; Buurma, Niklaas J.; Zhang, Xin-Xiang 收藏  |  浏览/下载：36/0  |  提交时间：2017/12/03 HUMAN TELOMERIC DNA  STRUCTURAL BASIS  BINDING  LIGAND  PROBE  DRUG  VISUALIZATION  OPTIMIZATION  COMPLEXES  BIOSENSOR   Antiamyloidogenic Activity of A beta 42-Binding Peptoid in Modulating Amyloid Oligomerization 期刊论文 SMALL, 2017 Zhao, Zijian; Zhu, Ling; Li, Haiyun; Cheng, Peng; Peng, Jiaxi; Yin, Yudan; Yang, Yang; Wang, Chen; Hu, Zhiyuan; Yang, Yanlian 收藏  |  浏览/下载：8/0  |  提交时间：2017/12/04 aggregation,amyloid oligomerization,antiamyloidogenic,inhibitor,peptoids  GAMMA-SECRETASE INHIBITORS  SMALL-MOLECULE INHIBITORS  ALZHEIMERS-DISEASE  BETA-PEPTIDE  FIBRIL FORMATION  PROTEIN AGGREGATION  MOUSE MODEL  MECHANISM  NEUROTOXICITY  CONFORMATION   Computational Multitarget Drug Design 期刊论文 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2017 Zhang, Weilin; Pei, Jianfeng; Lai, Luhua 收藏  |  浏览/下载：9/0  |  提交时间：2017/12/03 DE-NOVO DESIGN  PROTEIN-COUPLED RECEPTORS  TARGET PREDICTION  IN-SILICO  SMALL-MOLECULE  BINDING-SITES  POLYPHARMACOLOGICAL PROFILES  MULTIPLE LIGANDS  WEB SERVER  OLD DRUGS   A unique thermo-induced gel-to-gel transition in a pH-sensitive small-molecule hydrogel 期刊论文 SCIENTIFIC REPORTS, 2017 Xie, Hongtao; Ayoubi, Mehran Asad; Lu, Wensheng; Wang, Jide; Huang, Jianbin; Wang, Wei 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 WORMLIKE MICELLES  AGGREGATION BEHAVIOR  SURFACTANT  CHAIN  NANOPARTICLES  GELATION   Small molecule enabled chemical biology and drug discovery Preface 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017 Lei, Xiaoguang 收藏  |  浏览/下载：1/0  |  提交时间：2017/12/03