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An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domain 期刊论文
CELL DISCOVERY, 2016, 卷号: 2
作者:  Yin, Yanting;  Zhou, X. Edward;  Hou, Li;  Zhao, Li-Hua;  Liu, Bo
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Protective Role of PPARdelta in Lipoapoptosis of Pancreatic beta Cells 期刊论文
LIPIDS, 2016, 卷号: 51, 期号: 11, 页码: 1259-1268
作者:  Yang, Y;  Ren, JG;  Tong, YZ;  Hu, XJ;  Lv, QG
收藏  |  浏览/下载:4/0  |  提交时间:2017/05/08
Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 122, 页码: 382-393
作者:  Kondengaden, Shukkoor M.;  Luo, Liu-fei;  Huang, Kenneth;  Zhu, Mengyuan
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1359-1369
作者:  Ma, Shan-yao;  Ning, Meng-meng;  Zou, Qing-an;  Feng, Ying;  Ye, Yang-liang
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes 期刊论文
PHARMACOLOGICAL REVIEWS, 2016, 卷号: 68, 期号: 4, 页码: 954-1013
作者:  de Graaf, Chris;  Donnelly, Dan;  Wootten, Denise;  Lau, Jesper;  Sexton, Patrick M.
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
RNA-binding protein CUGBP1 regulates insulin secretion via activation of phosphodiesterase 3B in mice 期刊论文
DIABETOLOGIA, 2016, 卷号: 59, 期号: 9, 页码: 1959-1967
作者:  Zhai, Kui;  Gu, Lei;  Yang, Zhiguang;  Mao, Yang;  Jin, Meng
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 29, 页码: 15119-15130
作者:  Zhao, Li-Hua;  Yin, Yanting;  Yang, Dehua;  Liu, Bo;  Hou, Li
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
Intestinally-targeted TGR5 agonists equipped with quaternary ammonium have an improved hypoglycemic effect and reduced gallbladder filling effect 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Cao, Hua;  Chen, Zhi-Xiang;  Wang, Kai;  Ning, Meng-Meng;  Zou, Qing-An
收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R) 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 25, 页码: 12991-13004
作者:  Yang, Dehua;  de Graaf, Chris;  Yang, Linlin;  Song, Gaojie;  Dai, Antao
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Site-specific fatty chain-modified exenatide analogs with balanced glucoregulatory activity and prolonged in vivo activity 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 110, 页码: 80-91
作者:  Sun, Lidan;  Huang, Xun;  Han, Jing;  Cai, Xingguang;  Dai, Yuxuan
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08


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