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靶向肿瘤血管诱发血栓栓塞体系的建立及活性鉴定 期刊论文
2014
王显江; 王池真; 陈小丽; 李哲; 罗伶俐; 吕莎; 梅理祥; 周娇; 王生育; 颜江华
收藏  |  浏览/下载：1/0  |  提交时间：2016/05/17
光电及电化学发光传感器研究环境污染物导致的DNA特异性损伤 学位论文
博士, 北京: 中国科学院研究生院, 2014
作者:  吴一萍
收藏  |  浏览/下载：108/0  |  提交时间：2015/06/25
Exact tailoring of an ATP controlled streptavidin binding aptamer 期刊论文
RSC ADVANCES, 2014, 卷号: 4, 期号: 29, 页码: 15111-15114
作者:  Bing, Tao;  Mei, Hongcheng;  Zhang, Nan;  Qi, Cui;  Liu, Xiangjun
收藏  |  浏览/下载：8/0  |  提交时间：2019/04/09
Amplified voltammetric detection of glycoproteins using 4-mercaptophenylboronic acid/biotin-modified multifunctional gold nanoparticles as labels 期刊论文
International Journal of Nanomedicine, 2014, 卷号: 9, 期号: 1, 页码: 2619-2626
作者:  Liu, Lin*;  Xing, Yun;  Zhang, Hui;  Liu, Ruili;  Liu, Huijing
收藏  |  浏览/下载：56/0  |  提交时间：2019/12/03
Ultrasensitive detection of protein biomarkers is essential for early diagnosis and therapy of many diseases. Glycoproteins  differing from other types of proteins  contain carbohydrate moieties in the oligosaccharide chains. Boronic acid can form boronate ester covalent bonds with diol-containing species. Herein  we present a sensitive and cost-effective electrochemical method for glycoprotein detection using 4-mercaptophenylboronic acid (MBA)/biotin-modified gold nanoparticles (AuNPs) (MBA-biotin-AuNPs) as labels. To demonstrate the feasibility and sensitivity of this method  recombinant human erythropoietin (rHuEPO) was tested as a model analyte. Specifically  rHuEPO was captured by the anti-rHuEPO aptamer-covered electrode and then derivatized with MBA-biotin-AuNPs through the boronic acid–carbohydrate interaction. The MBA-biotin-AuNPs facilitated the attachment of streptavidin-conjugated alkaline phosphatase for the production of electroactive p-aminophenol from p-aminophenyl phosphate substrate. A detection limit of 8 fmol L-1 for rHuEPO detection was achieved. Other glycosylated and non-glycosylated proteins  such as horseradish peroxidase  prostate specific antigen  metallothionein  streptavidin  and thrombin showed no interference in the detection assay.  
Logic Nanoparticle Beacon Triggered by the Binding-Induced Effect of Multiple Inputs 期刊论文
acs applied materials interfaces, 2014
Yang, Jing; Dong, Chen; Dong, Yafei; Liu, Shi; Pan, Linqiang; Zhang, Cheng
收藏  |  浏览/下载：4/0  |  提交时间：2015/11/11
An electrochemical biosensor for the sensitive detection of specific DNA based on a dual-enzyme assisted amplification 期刊论文
http://dx.doi.org/10.1016/j.electacta.2014.10.092, 2014
Lin, Chunshui; Chen, Yiying; Cai, Zhixiong; Luo, Feng; Wang, Yiru; Chen,; 王翊如; 陈曦
收藏  |  浏览/下载：3/0  |  提交时间：2015/07/22
基于DNA折纸的DNA复制的单分子检测和表征 期刊论文
南方医科大学学报, 2014, 期号: 9, 页码: 1235-1240
王奇; 樊友杰; 李宾
收藏  |  浏览/下载：17/0  |  提交时间：2015/03/13
Streptavidin sensor and its sensing mechanism based on water-soluble fluorescence conjugated polymer 期刊论文
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2014, 卷号: 122
作者:  Chen, Yanguo;  Hong, Peng;  Xu, Baoming;  He, Zhike;  Zhou, Baohan
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05
A sensitive electrochemical biosensor for microRNA detection based on streptavidin-gold nanoparticles and enzymatic amplification 期刊论文
ANALYTICAL METHODS, 2014, 卷号: Vol.6 No.9, 页码: 2889-2893
作者:  Peng, Yunlin;  Jiang, Jianhui;  Yu, Ruqin
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/31
A sensitive electrochemical biosensor for microRNA detection based on streptavidin-gold nanoparticles and enzymatic amplification 期刊论文
ANALYTICAL METHODS, 2014, 卷号: Vol.6 No.9, 页码: 2889-2893
作者:  Peng, Yunlin;  Jiang, Jianhui;  Yu, Ruqin
收藏  |  浏览/下载：1/0  |  提交时间：2019/12/31

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