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中国医学科学院 北京... [3]
上海大学 [1]
上海中医药大学 [1]
湖南中医药大学 [1]
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期刊论文 [6]
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2019 [2]
2018 [3]
2017 [1]
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20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 4
作者:
Qin, Hong-You
;
Kang, Xiang-Ping
;
Hu, Hai-Yan
;
Zheng, Jing
;
Jiang, Jia-Ye
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/12/05
apoptosis
ATF4
endoplasmic reticulum stress (ER stress)
human umbilical vein endothelial cells (HUVECs)
protein kinase R-like endoplasmic reticulum kinase (PERK)
protopanaxadiol (PPD)
small interfering RNA (siRNA)
20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway
期刊论文
Journal of cellular biochemistry, 2019, 卷号: 120, 页码: 5085-5096
作者:
Wang Xue[1]
;
Xia Hua-Ying[2]
;
Qin Hong-You[3]
;
Kang Xiang-Ping[4]
;
Hu Hai-Yan[5]
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/04/22
ATF4
apoptosis
endoplasmic reticulum stress (ER stress)
human umbilical vein endothelial cells (HUVECs)
protein kinase R-like endoplasmic reticulum kinase (PERK)
protopanaxadiol (PPD)
small interfering RNA (siRNA)
The protective effect of 20(S)-protopanaxadiol (PPD) against chronic sleep deprivation (CSD)-induced memory impairments in mice
期刊论文
2018, 卷号: 137, 页码: 249-256
作者:
Lu, Cong
;
Lv, Jingwei
;
Dong, Liming
;
Jiang, Ning
;
Wang, Yan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/01/03
20(S)-Protopanaxadiol (PPD)
Chronic sleep deprivation(CSD)
Mice
Cognitive improvement
Cortex
Hippocampus
Oxidative stress
20(S)-protopanaxadiol (PPD) alleviates scopolamine-induced memory impairment via regulation of cholinergic and antioxidant systems, and expression of Egr-1, c-Fos and c-Jun in mice
期刊论文
2018, 卷号: 279, 页码: 64-72
作者:
Lu, Cong
;
Dong, Liming
;
Lv, Jingwei
;
Wang, Yan
;
Fan, Bei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
20(S)-Protopanaxadiol (PPD)
Scopolamine
Mice
Cholinergic function
Antioxidant system
Immediate early genes protein
Metabolic analysis of Panax notoginseng saponins with gut microbiota-mediated biotransformation by HPLC-DAD-Q-TOF-MS/MS
期刊论文
Journal of Pharmaceutical and Biomedical Analysis, 2018, 卷号: 150, 页码: 199-207
作者:
Chen, Man-Yun
;
Shao, Li
;
Zhang, Wei
;
Wang, Chong-Zhi
;
Zhou, Hong-Hao
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
ACN
acetonitrile
DAD
diode array-detector
DMSO
dimethyl sulphoxide
ESI
electrospray ionization
GAM
general anaerobic medium
GF1
ginsenoside F1
GC-K
ginsenoside compound K
GRh2
ginsenoside Rh2
HF-HP
high-fat and high-protein
HPLC-DAD-Q-TOF-MS/MS
high-performance liquid chromatography coupled with diode array detection/quadrupole tandem time-of-flight mass spectrometry
LF-PF
low-fat and plant fiber-rich
LLE
liquid-liquid extraction
PPD
protopanaxadiol
PPT
protopanaxatriol
PNS
Panax notoginseng saponins
RSDs
relative standard deviations
SEM
standard deviation of mean
TICs
total ion chromatograms
Panax notoginseng
Ginsenosides
Gut microbiota
Biotransformation
Metabolic profile
HPLCDAD-Q-TOF-MS/MS
Cytochromes P450 Inhibitory Excipient-Based Self-Microemulsions for the Improved Bioavailability of Protopanaxatriol and Protopanaxadiol: Preparation and Evaluation
期刊论文
2017, 卷号: 83, 期号: 5, 页码: 453-460
作者:
Yang, Feifei
;
Zhou, Jing
;
Liu, Chunyu
;
Hu, Xiao
;
Pan, Ruile
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/04
protopanaxatriol (PPT)
protopanaxadiol (PPD)
self-microemulsion
CYP450
oral bioavailability
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