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HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-15
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
LDGRNMF: LncRNA-disease associations prediction based on graph regularized non-negative matrix factorization
期刊论文
NEUROCOMPUTING, 2021, 卷号: 424, 期号: 2, 页码: 236-245
作者:
Wang, MN (Wang, Mei-Neng)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Wang, L (Wang, Lei)[ 2,3 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Zheng, K (Zheng, Kai)[ 4 ]
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/03/05
LncRNA-disease associations
LncRNA-disease similarity
Nonnegative matrix factorization
Graph regularization
A Novel Method to Predict Drug-Target Interactions Based on Large-Scale Graph Representation Learning
期刊论文
CANCERS, 2021, 卷号: 13, 期号: 9, 页码: 1-12
作者:
Zhao, BW (Zhao, Bo-Wei) 1 , 2 , 3
;
You, ZH (You, Zhu-Hong) 1 , 2 , 3
;
Hu, L (Hu, Lun) 1 , 2 , 3
;
Guo, ZH (Guo, Zhen-Hao) 1 , 2 , 3
;
Wang, L (Wang, Lei) 1 , 2 , 3
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/07/27
drug discoverydrug-target interactionslarge-scale graph representation learningcomputational method
DBMDA: A Unified Embedding for Sequence-Based miRNA Similarity Measure with Applications to Predict and Validate miRNA-Disease Associations
期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2020, 卷号: 19, 期号: 3, 页码: 602-611
作者:
Zheng, K (Zheng, Kai)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Wang, L (Wang, Lei)[ 2,3 ]
;
Zhou, Y (Zhou, Yong)[ 1 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
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  |  
浏览/下载:47/0
  |  
提交时间:2020/04/21
GCNCDA: A new method for predicting circRNA-disease associations based on Graph Convolutional Network Algorithm
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 5, 页码: 1-19
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, YM (Li, Yang-Ming)[ 3 ]
;
Zheng, K (Zheng, Kai)[ 4 ]
;
Huang, YA (Huang, Yu-An)[ 5 ]
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  |  
浏览/下载:26/0
  |  
提交时间:2020/07/06
iCDA-CGR: Identification of circRNA-disease associations based on Chaos Game Representation
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 5, 页码: 1-22
作者:
Zheng, K (Zheng, Kai)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/06
An efficient approach based on multi-sources information to predict circRNA-disease associations using deep convolutional neural network
期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 13, 页码: 4038-4046
作者:
Wang, L (Wang, Lei)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 1 ]
;
Huang, YA (Huang, Yu-An)[ 2 ]
;
Huang, DS (Huang, De-Shuang)[ 3 ]
;
Chan, KCC (Chan, Keith C. C.)[ 2 ]
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  |  
浏览/下载:15/0
  |  
提交时间:2020/09/09
Identification of potential drug-targets by combining evolutionary information extracted from frequency profiles and molecular topological structures
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 卷号: 96, 期号: 2, 页码: 758-767
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Yan, X (Yan, Xin)[ 3 ]
;
Zhang, W (Zhang, Wei)[ 1 ]
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  |  
浏览/下载:45/0
  |  
提交时间:2020/11/04
drug-target interaction
rotation forest
two-dimensional principal component analysis
Combining High Speed ELM Learning with a Deep Convolutional Neural Network Feature Encoding for Predicting Protein-RNA Interactions
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 3, 页码: 972-980
作者:
Wang, L (Wang, Lei)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Huang, DS (Huang, De-Shuang)[ 3 ]
;
Zhou, FF (Zhou, Fengfeng)[ 4,5 ]
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/09
Proteins
RNA
Convolution
Neural networks
Benchmark testing
Feature extraction
Sparse matrices
Convolution neural network
extreme learning machine
RNA-protein interactions
sequence
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