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Mechanistic Studies of a Nonheme Iron Enzyme OvoA in Ovothiol Biosynthesis Using a Tyrosine Analogue, 2-Amino-3-(4-hydroxy-3-(methoxyl) phenyl) Propanoic Acid (MeOTyr) 期刊论文
ACS CATALYSIS, 2019, 卷号: 9, 期号: 1
作者:  Chen, Li;  Naowarojna, Nathchar;  Chen, Bin;  Xu, Meiling;  Quill, Melissa
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/05
A novel recombinant RANKL vaccine prepared by incorporation of an unnatural amino acid into RANKL and its preventive effect in a murine model of collagen-induced arthritis. 期刊论文
International immunopharmacology, 2018, 卷号: 64, 页码: 326-332
作者:  Wu Tailin;  Li Feng;  Sha Xin;  Li Fuyang;  Zhang Bobo
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/26
A new vaccine targeting RANKL, prepared by incorporation of an unnatural Amino acid into RANKL, prevents OVX-induced bone loss in mice 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 499, 页码: 648-654
作者:  Li, Feng;  Li, Huan;  Zhai, Qian;  Li, Fuyang;  Wu, Tailin
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/26
Improved chemical synthesis of o-nirtrobenzyl-tyrosine for concise site-specific N-15-tyrosine NMR analysis demonstrated by plant ABA receptor PYL10 期刊论文
TETRAHEDRON LETTERS, 2017, 卷号: 58, 期号: 39, 页码: 3764-3767
作者:  Guo, Xiaoqi;  Zhang, Bo;  He, Yao;  Liu, Yangzhong;  Tian, Changlin
收藏  |  浏览/下载:23/0  |  提交时间:2018/08/17
Lanthanoid tagging via an unnatural amino acid for protein structure characterization 期刊论文
JOURNAL OF BIOMOLECULAR NMR, 2017, 卷号: 67, 期号: 4, 页码: 273-282
作者:  Gu, Xin-Hua;  Tang, Chun;  Dong, Xu;  Jiang, Wen-Xue
收藏  |  浏览/下载:19/0  |  提交时间:2017/11/24
Rational design of metalloenzymes: From single to multiple active sites 期刊论文
Coordination Chemistry Reviews, 2017, 卷号: 336, 期号: Volume 336, 页码: 1-27
作者:  Lin, Ying-Wu*
收藏  |  浏览/下载:22/0  |  提交时间:2019/12/27
UAAs  unnatural amino acids  Rd  rubredoxin  EPR  electron paramagnetic resonance  Az  azurin  SOR  superoxide reductase  PDB  protein data bank  6-PGLac  6-phosphogluconolactonase  H-bond  hydrogen-bond  NIR  nitrite reductase  ET  electron transfer  3SCC  three stranded coiled coil  Bpy-Ala  (2,2′-bipyridinine-5-yl)alanine  CcO  cytochrome c oxidase  N2OR  nitrous oxidase reductase  XANES  X-ray absorption near-edge structure  DF  Due Ferri  4-AP  4-amino-phenol  POP  prolyl oligopeptidase  ee  enantiomeric excess  HCO  heme-copper oxidase  NOR  nitric oxide reductase  MnP  manganese peroxidase  Mb  myoglobin  RFQ-rR  freeze-quench resonance Raman  CcP  Cyt c peroxidase  BMC  microcompartment  CYP  cytochrome P450  TON  turnover number  TDHC  tetradehydrocorrin  NB  nitrobindin  RCM  ring-closing metathesis  ROMP  ring-opening metathesis polymerization  SAV  steptavidin  NCS  neocarzinostatin  BLG  -Lactoglobulin  HSA  human serum albumin  BSA  bovine serum albumin  ITC  isothermal titration calorimetry  AldO  alditol oxidase  FAD  flavin adenine dinucleotide  MP  microperoxidase  HB  heme-binding  GTL  Geobacillus thermocatenulatus lipase  4NPA  4-nitrophenyl acetate  LmrR  Lactococcal multidrug resistance Regulator  ABTS  2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt  mCPBA  meta-chloroperbenzoic acid  Fd  ferredoxin  Fld  flavodoxin  HTHP  hexameric Tyr-coordinated heme protein  AFM  atomic force microscopy  TEM  transmission electron microscopy  MRI  magnetic resonance imaging  Metalloproteins  Metalloenzymes  Protein design  Multiple active sites  Biocatalysts  
Design and Synthesis of a Novel Series of Opioid Dipeptides and Evaluation of Their Analgesic Effect in Vivo 期刊论文
ACTA CHIMICA SINICA, 2016, 卷号: 74, 期号: 1, 页码: 44-48
作者:  Liu, X;  Zhao, L;  Wang, Y;  Mou, LY;  Zhang, YX
收藏  |  浏览/下载:110/0  |  提交时间:2017/01/10
Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 22, 页码: 5393-5397
作者:  Liu, X;  Zhao, L;  Wang, Y;  Mou, LY;  Yang, JX
收藏  |  浏览/下载:5/0  |  提交时间:2017/01/13
Characterization of (R)-selective amine transaminases identified by in silico motif sequence blast 期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2015, 卷号: 99, 期号: 6, 页码: 2613-2621
作者:  Jiang, Jinju;  Chen, Xi;  Zhang, Dalong;  Wu, Qiaqing;  Zhu, Dunming
收藏  |  浏览/下载:32/0  |  提交时间:2016/06/23
A highly efficient approach to unnatural amino-acids containing 3-hydroxyoxindole skeleton via a one-pot, three-component procedure 期刊论文
TETRAHEDRON LETTERS, 2015, 卷号: 56, 期号: 4, 页码: 586-589
作者:  Huang, Huang;  Xu, Yong;  Mao, Fei;  Zhu, Jin;  Jiang, Hualiang
收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08


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