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上海药物研究所 [18]
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期刊论文 [42]
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浏览/检索结果:
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Short-term outcomes of laparoscopy-assisted versus open surgery for low rectal cancer (LASRE): A multicenter, randomized, controlled trial.
期刊论文
JOURNAL OF CLINICAL ONCOLOGY, 2022, 卷号: 40
作者:
Chi, Pan
;
Su, Xiangqian
;
Xu, Jianmin
;
Qiu, Huizhong
;
Wang, Ziqiang
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:
Liu, Xiao
;
Yang, Su
;
Hart, Jonathan R.
;
Xu, Yingna
;
Zou, Xinyu
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/04
phosphoinositide 3-kinase (PI3K)
activation
inhibition
activity-dependent conformational changes
Non-invasive skin cholesterol testing: a potential proxy for LDL-C and apoB serum measurements
期刊论文
LIPIDS IN HEALTH AND DISEASE, 2021, 卷号: 20
作者:
Lai, Jiacheng
;
Han, Yongsheng
;
Huang, Chongjian
;
Li, Bin
;
Ni, Jingshu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/11/15
Lipid management
LDL-C
apoB
Skin cholesterol
Low initial LDL-C
Constitutive signal bias mediated by the human GHRHR splice variant 1
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Fulai
;
Zhang, Chao
;
Zou, Xinyu
;
Zhang, Huibing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/01
class B1 GPCR
receptor bias
cancer
cell proliferation
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
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  |  
浏览/下载:43/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin
Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 32, 页码: 8
作者:
Wang, Xi
;
Cheng, Xi
;
Zhao, Lihua
;
Wang, Yuzhe
;
Ye, Chenyu
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/11/04
parathyroid hormone receptor 2
cryo-electron microscopy
G protein-coupled receptor
ligand recognition
syndromic short stature
Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
ELIFE, 2021, 卷号: 10, 页码: 20
作者:
Zhao, Fenghui
;
Zhang, Chao
;
Zhou, Qingtong
;
Hang, Kaini
;
Zou, Xinyu
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/08/17
Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening
期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:
Zhou, Qingtong
;
Guo, Wanjing
;
Dai, Antao
;
Cai, Xiaoqing
;
Vass, Marton
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/08/17
GLP-1R
virtual screening
allosteric modulator
drug discovery
molecular docking
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:
Cong, Zhaotong
;
Chen, Li-Nan
;
Ma, Honglei
;
Zhou, Qingtong
;
Zou, Xinyu
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/08/17
Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket
期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:
Lu, Yan
;
Liu, Hongyue
;
Yang, Dehua
;
Zhong, Li
;
Xin, Ye
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
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