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浏览/检索结果: 共8条，第1-8条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang 收藏  |  浏览/下载：60/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity 期刊论文 JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 329, 页码: 1249-1261 作者:  Zhao, Pengfei;  Zhang, Jiaxin;  Wu, Aihua;  Zhang, Meng;  Zhao, Yuge 收藏  |  浏览/下载：107/0  |  提交时间：2021/05/24 Brain targeting delivery  Tumor-associated macrophage  Osimertinib resistance  Brain metastasis  Innate immunity  Combination therapy   Successful treatment with osimertinib and its subsequent resistance mechanism in a patient with non-small-cell lung cancer harboring acquired EGFR T790M mutation after recovery from AC0010-induced interstitial lung disease 期刊论文 2019, 卷号: 12, 页码: 5545-5549 作者:  Wang, Hanping;  Zhang, Li;  Shi, Xiaohua;  Zhang, Xiaotong;  Si, Xiaoyan 收藏  |  浏览/下载：10/0  |  提交时间：2020/01/03 osimertinib  AC0010  interstitial lung disease  resistance mechanism  transformation  large-cell neuroendocrine carcinoma   Co-mutational assessment of circulating tumour DNA (ctDNA) during osimertinib treatment for T790M mutant lung cancer 期刊论文 2019 作者:  Xing Puyuan;  Han Xiaohong;  Wang Sha;  Liu Yutao;  Yang Sheng 收藏  |  浏览/下载：21/0  |  提交时间：2020/01/03 circulating tumour DNA  non-small-cell lung cancer  osimertinib  resistance   Heterogeneity-based, multiple mechanisms in the resistance to osimertinib (AZD9291): A case report 期刊论文 2018, 卷号: 9, 期号: 4, 页码: 498-501 作者:  Liu, Yutao;  Hao, Xuezhi;  Hu, Xingsheng;  Li, Junling;  Wang, Yan 收藏  |  浏览/下载：6/0  |  提交时间：2020/01/03 Epidermal growth factor receptor T790 mutation  heterogeneity  MET amplification  osimertinib  resistance   Acquired &ITEGFR&IT L718V mutation mediates resistance to osimertinib in non-small cell lung cancer but retains sensitivity to afatinib 期刊论文 2018, 卷号: 118, 页码: 1-5 作者:  Liu, Yutao;  Li, Yan;  Ou, Qiuxiang;  Wu, Xue;  Wang, Xiaonan 收藏  |  浏览/下载：2/0  |  提交时间：2020/01/03 EGFR  L718V  Osimertinib  Afatinib  Resistance  NSCLC   Resistance Mechanisms of Osimertinib in Chinese Non-Small Cell Lung Cancer patients: Analysis from AURA17 Trial 期刊论文 2018, 卷号: 13, 期号: 10, 页码: S345-S345 作者:  Zhou, C.;  Hu, M.;  Zhu, X.;  Sun, Y.;  Lu, X. 收藏  |  浏览/下载：1/0  |  提交时间：2020/01/03 non-small cell lung cancer  osimertinib  resistance mechanisms   Synthesis and evaluation of osimertinib derivatives as potent EGFR inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017 Gao, Hongying; Yang, Zimo; Yang, Xinglin; Rao, Yu 收藏  |  浏览/下载：7/0  |  提交时间：2017/12/03 Osimertinib  N-Oxide metabolites  Fluoride  Non-small cell lung cancer  Epidermal growth factor receptor-tyrosine kinase inhibitors  CELL LUNG-CANCER  FACTOR RECEPTOR EGFR  MEDICINAL CHEMISTRY  TARGETED THERAPY  DRUG DISCOVERY  RESISTANCE  FLUORINE  MUTATIONS  MUTANT  PHARMACOKINETICS