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浏览/检索结果: 共4条，第1-4条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia 期刊论文 CHEMMEDCHEM, 2021, 页码: 12 作者:  Jin, Tingting;  Wang, Peipei;  Long, Xiubing;  Jiang, Kailong;  Song, Pinrao 收藏  |  浏览/下载：133/0  |  提交时间：2021/05/24 CHK1 inhibitor  diaminopyrimidine  DNA damage response  oral bioavailability   Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62 作者:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting 收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 CHK1 kinase inhibitor  Selectivity  Monotherapy  Hematologic malignancies   Design, synthesis and biological evaluation of thienopyridinones as Chk1 inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 17, 页码: 4882-4892 作者:  Song, Pinrao;  Peng, Peng;  Han, Mengmeng;  Cao, Xianchao;  Ma, Xiaodong 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Chk1 inhibitor  Thienopyridinones  Antitumor  Cell synergy   Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity 期刊论文 CANCER BIOLOGY & THERAPY, 2008, 卷号: 7, 期号: 11, 页码: 1726-1731 作者:  Feng, Jian-Ming;  Zhu, Hong;  Zhang, Xiao-Wei;  Ding, Jian;  Miao, Ze-Hong 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 topoisomerase II inhibitor  naphthalimide  R16  colon carcinoma  Chk1  proteasome  anticancer activity