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上海药物研究所 [8]
南京地理与湖泊研究所 [3]
地理科学与资源研究所 [2]
海洋研究所 [2]
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期刊论文 [21]
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2021 [21]
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Drug target inference by mining transcriptional data using a novel graph convolutional network framework
期刊论文
PROTEIN & CELL, 2021, 页码: 21
作者:
Zhong, Feisheng
;
Wu, Xiaolong
;
Yang, Ruirui
;
Li, Xutong
;
Wang, Dingyan
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  |  
浏览/下载:21/0
  |  
提交时间:2021/12/01
drug target inference
transcriptomics
deep learning
experimental verification
A new meta-coupling framework to diagnose the inequity hidden in China's cultivated land use
期刊论文
ENVIRONMENTAL SCIENCE & POLICY, 2021, 卷号: 124, 页码: 635-644
作者:
Chuai, Xiaowei
;
Gao, Runyi
;
Li, Jianbao
;
Guo, Xiaomin
;
Lu, Qinli
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  |  
浏览/下载:97/0
  |  
提交时间:2021/11/05
Agriculture
Cultivated land
Inequity
Meta-coupling
Input-output
China
Vertical distribution changes in land cover between 1990 and 2015 within the Koshi River Basin, Central Himalayas
期刊论文
JOURNAL OF GEOGRAPHICAL SCIENCES, 2021, 卷号: 31, 期号: 10, 页码: 1419-1436
作者:
Wu Xue
;
Paudel Basanta
;
Zhang Yili
;
Liu Linshan
;
Wang Zhaofeng
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  |  
浏览/下载:31/0
  |  
提交时间:2021/11/05
vertical belt
land cover
Central Himalayas
Koshi River Basin
climate change
Structural insights into the activation of human calcium-sensing receptor
期刊论文
ELIFE, 2021, 卷号: 10, 页码: 24
作者:
Chen, Xiaochen
;
Wang, Lu
;
Cui, Qianqian
;
Ding, Zhanyu
;
Han, Li
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  |  
浏览/下载:66/0
  |  
提交时间:2021/11/04
G-protein-coupled receptor
calcium-sensing receptor
cryo-electron microscopy
calcium ions
nanobody
CaSR
GPCR
cryo-EM
None
Facing small and biased data dilemma in drug discovery with enhanced federated learning approaches
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2021, 页码: 11
作者:
Xiong, Zhaoping
;
Cheng, Ziqiang
;
Lin, Xinyuan
;
Xu, Chi
;
Liu, Xiaohong
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  |  
浏览/下载:43/0
  |  
提交时间:2021/11/04
federated learning
drug discovery
FedAMP
Non-IID data
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis
期刊论文
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:
Liu, Ping
;
Cong, Xiaoji
;
Liao, Shengjie
;
Jia, Xinglong
;
Wang, Xiaomin
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  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
Identification of novel anti-inflammatory Nur77 modulators by virtual screening
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7
作者:
Ding, Xiaoyu
;
Zhao, Zijie
;
Wu, Yue
;
Zhang, Hao
;
Chen, Kaixian
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  |  
浏览/下载:43/0
  |  
提交时间:2021/08/17
Nur77
Binding site evaluation
Virtual Screening
Inflammation
East Asian monsoon intensification promoted weathering of the magnesium-rich southern China upper crust and its global significance
期刊论文
SCIENCE CHINA-EARTH SCIENCES, 2021, 页码: 16
作者:
Yang, Yibo
;
Galy, Albert
;
Fang, Xiaomin
;
France-Lanord, Christian
;
Wan, Shiming
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  |  
浏览/下载:27/0
  |  
提交时间:2021/12/07
Tibetan Plateau
Late Oligocene
Silicate weathering
Carbon cycle
Oceanic Mg cycle
Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 6
作者:
Xiong, Fengmin
;
Ding, Xiaoyu
;
Zhang, Hao
;
Luo, Xiaomin
;
Chen, Kaixian
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/08/17
Monoacylglycerol lipase
Inhibitor
Virtual screening
Inflammation
Concise and efficient direct-view generation of arbitrary cylindrical vector beams by a vortex half-wave plate
期刊论文
PHOTONICS RESEARCH, 2021, 卷号: 9
作者:
Qi, Junli
;
Wang, Weihua
;
Shi, Bo
;
Zhang, Hui
;
Shen, Yanan
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  |  
浏览/下载:70/0
  |  
提交时间:2021/06/15
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