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科研机构
上海药物研究所 [19]
内容类型
期刊论文 [19]
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2021 [3]
2020 [2]
2019 [3]
2018 [1]
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Triptolide analog LLDT-8 ameliorates psoriasis-like dermatitis in BALB/c mice via suppressing the IL-36 alpha signaling pathway
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Qi, Qing
;
Li, Qian
;
Zhu, Hongwen
;
Lu, Huimin
;
Yang, Xiaoqian
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/08/17
Triptolide
LLDT-8
Psoriasis
IL-36 alpha
IL-36 alpha pathway
Inflammation
A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 120, 页码: 12
作者:
Huang, Suling
;
Wu, Yanwei
;
Zhao, Zhuohui
;
Wu, Bing
;
Sun, Kai
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2021/08/17
Macrophage
NLRP3 inflammasome
Hepatic lipid accumulation
NASH
FXR
Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 94, 页码: 11
作者:
Wu, Bing
;
Wu, Yanwei
;
Fan, Chen
;
Feng, Chunlan
;
Wang, Haoyu
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/06/11
SLE
Lupus nephritis
Heme
Inflammation
Oxidative damage
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way
期刊论文
FASEB JOURNAL, 2020, 页码: 16
作者:
Wu, Yanwei
;
Wu, Bing
;
Zhang, Zongwang
;
Lu, Huimin
;
Fan, Chen
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
IBD
M1
M2
ulcerative colitis
RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 172, 页码: 16
作者:
Lu, Huimin
;
Li, Heng
;
Fan, Chen
;
Qi, Qing
;
Yan, Yuxi
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
RIPK1 inhibitor
Colitis
Barrier homeostasis
IECs-immunocytes crosstalk
Necroptosis
NF-kappa B
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:
Zhang, Zongwang
;
Wu, Yanwei
;
Wu, Bing
;
Qi, Qing
;
Li, Heng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Systemic sclerosis
SAHH inhibitor
Fibrosis
Inflammation
Vasculopathy
TGF-beta
Heme Catabolic Pathway in Inflammation and Immune Disorders
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:
Wu, Bing
;
Wu, Yanwei
;
Tang, Wei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
heme
heme oxygenase
carbon monoxide
biliverdin
inflammation
immune disorders
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2209-2226
作者:
Li, Heng
;
Fan, Chen
;
Feng, Chunlan
;
Wu, Yanwei
;
Lu, Huimin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
artemisininanaloguesm934amelioratesdssinducedmouseulcerativecolitisviasuppressingneutrophilsandmacrophages
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 10, 页码: 1633
作者:
Yan Yuxi
;
Shao Meijuan
;
Qi Qing
;
Xu Yansheng
;
Yang Xiaoqian
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
NF-KAPPA-B
SODIUM-INDUCED COLITIS
MURINE COLITIS
MICE
CYTOKINES
CELLS
SM934
artemisinin analogue
ulcerative colitis
inflammatory bowel disease (IBD)
neutrophils macrophage
NF-kappa B
RAW 2647 cells
THP-1-derived macrophages
Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation
期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2016, 卷号: 13, 期号: 3, 页码: 379-390
作者:
Wu, Yanwei
;
He, Shijun
;
Bai, Bingxin
;
Zhang, Luyao
;
Xue, Lu
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
B cell
plasma cell
SM934
systemic lupus erythematosus
Toll-like receptor
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