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Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo
收藏  |  浏览/下载:39/0  |  提交时间:2022/01/18
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载:91/0  |  提交时间:2021/11/04
Discovery of a Potent and Selective NF-kappa B-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4388-4407
作者:  Li, Zhiqiang;  Li, Xinzhi;  Su, Ming-Bo;  Gao, Li-Xin;  Zhou, Yu-Bo
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/01
Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 2, 页码: 804-815
作者:  Zhang, Shu-Wei;  Gong, Chao-Jun;  Su, Ming-Bo;  Chen, Fei;  He, Ting
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/01
Novel spirocyclic tranylcypromine derivatives as lysine-specific demethylase 1 (LSD1) inhibitors 期刊论文
RSC ADVANCES, 2018, 卷号: 8, 期号: 3, 页码: 1666-1676
作者:  Shi, Ying;  Wu, Yan-Ran;  Su, Ming-Bo;  Shen, Dong-Hao;  Gunosewoyo, Hendra
收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112
作者:  Ji, Yue-Yang;  Lin, Sen-Dong;  Wang, Yu-Jie;  Su, Ming-Bo;  Zhang, Wei
收藏  |  浏览/下载:19/0  |  提交时间:2019/01/08
Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials 期刊论文
CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56
作者:  Yuan, Bo;  Ye, Na;  Song, Shan-Shan;  Wang, Yu-Ting;  Song, Zilan
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
Design, synthesis and biological evaluation of bisthiazole-based trifluoromethyl ketone derivatives as potent HDAC inhibitors with improved cellular efficacy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 112, 页码: 81-90
作者:  Gong, Chao-Jun;  Gao, An-Hui;  Zhang, Yang-Ming;  Su, Ming-Bo;  Chen, Fei
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
Potent and Orally Efficacious Bisthiazole-Based Histone Deacetylase Inhibitors 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 6, 页码: 628-633
作者:  Chen, Fei;  Chai, Hui;  Su, Ming-Bo;  Zhang, Yang-Ming;  Li, Jia
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Curcusone D, a novel ubiquitin-proteasome pathway inhibitor via ROS-induced DUB inhibition, is synergistic with bortezomib against multiple myeloma cell growth 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2014, 卷号: 1840, 期号: 6, 页码: 2004-2013
作者:  Cao, Mei-Na;  Zhou, Yu-Bo;  Gao, An-Hui;  Cao, Jia-Yi;  Gao, Li-Xin
收藏  |  浏览/下载:33/0  |  提交时间:2019/01/08


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