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科研机构
上海药物研究所 [20]
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期刊论文 [20]
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2021 [2]
2020 [6]
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Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:
Hu, Ke
;
Li, Bo
;
Ma, Ruye
;
Yi, Hongfei
;
Xu, Zhijian
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/06/11
caspase
cell proliferation
cell cycle arrest
diffuse large B-cell lymphoma
PI3K-AKT-mTOR/JNK pathway
A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2021, 卷号: 13, 期号: 10, 页码: 11439-11449
作者:
Bu, Wenxuan
;
Li, Bo
;
Feng, Lijin
;
Feng, Qilin
;
Hu, Ke
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/12/16
Multiple myeloma
DCZ0858
mTOR
bone marrow microenvironment
cell proliferation
cell apoptosis
A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe
期刊论文
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:
Hu,Liangning
;
Li,Bo
;
Chen,Gege
;
Song,Dongliang
;
Xu,Zhijian
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/07/01
Multiple myeloma
Drug-resistance
DNA damage response
Cell cycle
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib
期刊论文
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:
Chen, Gege
;
Hu, Ke
;
Sun, Haiguo
;
Zhou, Jinfeng
;
Song, Dongliang
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2020/07/01
Multiple myeloma
Bone marrow microenvironment
DNA damage
JAK2/STAT3 pathway
A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11
作者:
Lu, Kang
;
Li, Bo
;
Zhang, Hui
;
Xu, Zhijian
;
Song, Dongliang
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/07/01
Antitumor effects of rafoxanide in diffuse large B cell lymphoma via the PTEN/PI3K/Akt and JNK/c-Jun pathways
期刊论文
LIFE SCIENCES, 2020, 卷号: 243, 页码: 11
作者:
He, Wan
;
Xu, Zhijian
;
Song, Dongliang
;
Zhang, Hui
;
Li, Bo
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/07/01
Diffuse large B-cell lymphoma
Rafoxanide
PTEN/PI3K/AKT
Apoptosis
DNA damage
A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression
期刊论文
CANCER RESEARCH, 2020, 卷号: 80, 期号: 3, 页码: 536-548
作者:
Wang, Yingcong
;
Huang, Jing
;
Li, Bo
;
Xue, Han
;
Tricot, Guido
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
Glycolysis is suppressed by DCZ0801-induced inactivation of the Akt/mTOR pathway in Multiple Myeloma
期刊论文
JOURNAL OF CANCER, 2020, 卷号: 11, 期号: 16, 页码: 4907-4916
作者:
Feng, Qilin
;
Yao, Qingchun
;
Li, Bo
;
Xie, Yongsheng
;
Zhang, Hui
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/12/24
DCZ0801
multiple myeloma
apoptosis
cell cycle
glycolysis
DCZ0801, a novel compound, induces cell apoptosis and cell cycle arrest via MAPK pathway in multiple myeloma
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2019, 卷号: 51, 期号: 5, 页码: 517-523
作者:
Zhang, Ting
;
Li, Bo
;
Feng, Qilin
;
Xu, Zhijian
;
Huang, Cheng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
DCZ0801
multiple myeloma
apoptosis
cell cycle
MAPK
dcz0801anovelcompoundinducescellapoptosisandcellcyclearrestviamapkpathwayinmultiplemyeloma
期刊论文
actabiochimicaetbiophysicasinica, 2019, 卷号: 51, 期号: 5, 页码: 517
作者:
Zhang Ting
;
Li Bo
;
Feng Qilin
;
Xu Zhijian
;
Huang Cheng
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
IN-VITRO
PTEROSTILBENE
CANCER
PROLIFERATION
P38
ACTIVATION
INDUCTION
SURVIVAL
ERK1/2
DCZ0801
multiple myeloma
apoptosis
cell cycle
MAPK
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