CORC

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CORC

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Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
收藏  |  浏览/下载：87/0  |  提交时间：2021/11/04
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载：71/0  |  提交时间：2021/08/17
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
收藏  |  浏览/下载：111/0  |  提交时间：2021/05/24
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:  Xi, Mengyu;  He, Wan;  Li, Bo;  Zhou, Jinfeng;  Xu, Zhijian
收藏  |  浏览/下载：41/0  |  提交时间：2020/12/24
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:  Xi, Mengyu;  He, Wan;  Li, Bo;  Zhou, Jinfeng;  Xu, Zhijian
收藏  |  浏览/下载：20/0  |  提交时间：2020/12/24
A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression 期刊论文
CANCER RESEARCH, 2020, 卷号: 80, 期号: 3, 页码: 536-548
作者:  Wang, Yingcong
收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
收藏  |  浏览/下载：91/0  |  提交时间：2020/07/01
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2 期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 4797-4808
作者:  Kong, Yuanyuan;  Li, Bo;  Chang, Shuaikang;  Gao, Lu;  Xu, Zhijian
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Rafoxanide, an organohalogen drug, triggers apoptosis and cell cycle arrest in multiple myeloma by enhancing DNA damage responses and suppressing the p38 MAPK pathway 期刊论文
Cancer letters, 2018, 卷号: 444, 页码: 45-59
作者:  Xiao, Wenqin;  Xu, Zhijian;  Chang, Shuaikang;  Li, Bo;  Yu, Dandan
收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08
Preclinical activity of DCZ3301, a novel aryl-guanidino compound in the therapy of multiple myeloma 期刊论文
THERANOSTICS, 2017, 卷号: 7, 期号: 15, 页码: 3690-3699
作者:  Gao, Minjie;  Li, Bo;  Sun, Xi;  Zhou, Yunfei;  Wang, Yingcong
收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08

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