QQ客服 官方微博 反馈留言

浏览/检索结果: 共4条，第1-4条 帮助 限定条件 专题：华中师范大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 In silico screening of a novel scaffold for fructose-1,6-bisphosatase (FBPase) inhibitors 期刊论文 Journal of Molecular Graphics and Modelling, 2019, 卷号: 86, 页码: 142-148 作者:  Huang, Yunyuan;  Chi, Bo;  Xu, Yanhong;  Song, Rongrong;  Wei, Lin 收藏  |  浏览/下载：32/0  |  提交时间：2019/12/23 Fructose-1,6-bisphosphate (FBPase)  FBPase inhibitors  DOX2.0  FBPase  fructose-1,6-bisphosphatase  FBP  fructose-1,6-biphosphate  IC50  half maximal inhibitory concentration  PAINS  Pan Assay Interference  T2D  Type 2 diabetes  SAR  structure−activity relationship  EGP  endogenous glucose production  GNG  gluconeogenesis  AMP  adenosine monophosphate  DOX  Docking ONIOM eXtended ONIOM (XO)  DOX2.0  Docking PM7@Mopac XO2  LE  ligand efficiency  LELP  lipophilicity-corrected ligand efficiency   New insight into the binding modes of TNP-AMP to human liver fructose-1,6-bisphosphatase 期刊论文 Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2016, 卷号: 165, 页码: 155-160 作者:  Han, Xinya;  Huang, Yunyuan;  Zhang, Rui;  Xiao, San;  Zhu, Shuaihuan 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/23 FBPase  fructose-1,6-bisphosphatase  TNP-AMP  2′,3′-O-(2,4,6-trinitrophenyl)adenosine 5′-monophosphate  FBP  fructose 1,6-bisphosphate  AMP  adenosine monophosphate  FDP  fructose-2,6-bisphosphate  F6P  fructose 6-phosphate  Fructose-1,6-bisphosphatase  TNP-AMP binding site  Active site  Allosteric site  Inhibitor binding site   Design, synthesis and evaluation of novel 5-phenylpyridin-2(1H)-one derivatives as potent reversible Bruton's tyrosine kinase inhibitors 期刊论文 Bioorganic and Medicinal Chemistry, 2015, 卷号: 23, 期号: 2, 页码: 348-364 作者:  Zhao, Xinge;  Xin, Minhang;  Huang, Wei;  Ren, Yanliang;  Jin, Qiu 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/23 Reversible Btk inhibitors  Structure  SAR  Efficacy  In vivo   Pharmacophore-based virtual screening and experimental validation of novel inhibitors against cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase 期刊论文 Journal of Chemical Information and Modeling, 2014, 卷号: 54, 期号: 3, 页码: 894-901 作者:  Sun, Yao;  Zhang, Rui;  Li, Ding;  Feng, Lingling*;  Wu, Di 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23