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浏览/检索结果: 共26条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位    发表日期：2017     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Curvularin derivatives from the soil-derived fungus Aspergillus polyporicola PSU-RSPG187 期刊论文 PHYTOCHEMISTRY LETTERS, 2017, 卷号: 22, 页码: 122-127 作者:  Choochuay, Jutatip;  Xu, Xin;  Rukachaisirikul, Vatcharin;  Guedduaythong, Piyada;  Phongpaichit, Souwalak 收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Aspergillus polyporicola  Cytochalasins  Curvularins  Soil-derived fungi  Antimicrobial activity  Cytotoxic activity   Cytosporone derivatives from the endophytic fungus Phomopsis sp PSU-H188 期刊论文 PHYTOCHEMISTRY LETTERS, 2017, 卷号: 22, 页码: 219-223 作者:  Kongprapan, Thippaya;  Xu, Xin;  Rukachaisirikul, Vatcharin;  Phongpaichit, Souwalak;  Sakayaroj, Jariya 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Phomopsis sp.  Hevea brasiliensis  Cytosporone  Antibacterial activity  Cytotoxic activity  Glucose output inhibitory activity  Protection of pancreatic beta-cells   Preparation of 5 '-deoxy-5 '-amino-5 '-C-methyl adenosine derivatives and their activity against DOT1L 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 22, 页码: 4960-4963 作者:  Liu, Tongchao;  Xie, Wuchen;  Li, Cong;  Ren, Huanming;  Mao, Yudong 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 5'-Deoxy-5'-amino-5'-C-methyl adenosine derivative  N-glycosylation  Nucleoside synthesis  DOT1L inhibitor  Structure activity relationship   Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 页码: 128-152 作者:  Wang, Zhengyu;  Shi, Xiaofan;  Zhang, Huan;  Yu, Liang;  Cheng, Yanhua 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Type 2 diabetes mellitus  Hypoglycemia  Dyslipidemia  Glucokinase activators  N-Thiazol-2-yl-benzamides   Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang 收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 176-195 作者:  Hu, Jianping;  Wang, Yingqing;  Li, Yanlian;  Xu, Lin;  Cao, Danyan 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 BRD4 inhibitor  Kinase  BI-2536  Dihydroquinoxalin-2(1H)-one   Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916 作者:  Xiamuxi, Hainimu;  Wang, Zhen;  Li, Jianfeng;  Wang, Yu;  Wu, Chunhui 收藏  |  浏览/下载：119/0  |  提交时间：2019/01/08 Dopamine  Serotonin  Multireceptor  Atypical antipsychotic  5-HT1A   G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin 期刊论文 NATURE COMMUNICATIONS, 2017, 卷号: 8 作者:  Wang, Ya-fang;  Zhang, Jie;  Su, Yi;  Shen, Yan-yan;  Jiang, Dong-xian 收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08 Selective targeting p53(WT) lung cancer cells harboring homozygous p53 Arg72 by an inhibitor of CypA 期刊论文 ONCOGENE, 2017, 卷号: 36, 期号: 33, 页码: 4719-4731 作者:  Lu, W.;  Cheng, F.;  Yan, W.;  Li, X.;  Yao, X. 收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08 DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway 期刊论文 JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169 作者:  Zhou, Ting-Ting;  Ma, Fei;  Shi, Xiao-Fan;  Xu, Xin;  Du, Te 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Gaq signaling  hepatic gluconeogenesis  protein kinase B (AKT)  type 2 diabetes mellitus (T2DM)