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浏览/检索结果: 共35条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位    内容类型：期刊论文    发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, synthesis, and bioactivity evaluation of novel Bcl-2/HDAC dual-target inhibitors for the treatment of multiple myeloma 期刊论文 Bioorganic & medicinal chemistry letters, 2018 作者:  Zhou, Ruolan;  Fang, Shaoyu;  Zhang, Minmin;  Zhang, Qingsen;  Hu, Jian 收藏  |  浏览/下载：97/0  |  提交时间：2019/01/08 Positive Allosteric Modulation of AMPAR by PF-4778574 Produced Rapid Onset Antidepressant Actions in Mice 期刊论文 Cerebral cortex (New York, N.Y. : 1991), 2018 作者:  Shen, Mengxin;  Lv, Dan;  Li, Shuting;  Zhang, Yanhua;  Wang, Zhen 收藏  |  浏览/下载：104/0  |  提交时间：2019/01/08 Deficiency of β-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases 期刊论文 Journal of immunology (Baltimore, Md. : 1950), 2018 作者:  Cai, Yingying;  Yang, Cuixia;  Yu, Xiaohan;  Qian, Jie;  Dai, Min 收藏  |  浏览/下载：148/0  |  提交时间：2019/01/08 Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction 期刊论文 European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 597-609 作者:  Chen, Danqi;  Chen, Yuehong;  Lian, Fulin;  Chen, Liu;  Li, Yanlian 收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08 Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文 European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689 作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao 收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08 The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors 期刊论文 Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842 作者:  Wang, Xinyi;  Ai, Jing;  Liu, Hongyan;  Peng, Xia;  Chen, Hui 收藏  |  浏览/下载：135/0  |  提交时间：2019/01/08 1,4-Diaryl-2-azetidinone  Combretastatin A-4  Tubulin polymerization  Antitumor   Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors 期刊论文 European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 281-294 作者:  Xing, Jing;  Zhang, Rukang;  Jiang, Xiangrui;  Hu, Tianwen;  Wang, Xinjun 收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08 Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1768-1776 作者:  Liu, Ying-Qiang;  Wang, Ya-Nan;  Lu, Xiao-Yun;  Tong, Lin-Jiang;  Li, Yan 收藏  |  浏览/下载：110/0  |  提交时间：2019/01/08 CSF-1R  small-molecule inhibitor  macrophage  myeloid leukemia   Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 428-441 作者:  Zhang, Qiumeng;  Shen, Qianqian;  Gao, Lixin;  Tong, Linjiang;  Li, Jia 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 Aurora A  Aurora B  KDR  Multi-targeted  Anticancer  Heterocyclic   Essential roles of neuropeptide VGF regulated TrkB/mTOR/BICC1 signaling and phosphorylation of AMPA receptor subunit GluAl in the rapid antidepressant-like actions of ketamine in mice 期刊论文 BRAIN RESEARCH BULLETIN, 2018, 卷号: 143, 页码: 58-65 作者:  Shen, Mengxin;  Lv, Dan;  Liu, Xu;  Li, Shuting;  Chen, Yaping 收藏  |  浏览/下载：112/0  |  提交时间：2019/01/08 VGF  Ketamine  TrkB  mTOR  BICC1