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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13 作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun 收藏  |  浏览/下载：30/0  |  提交时间：2021/12/01 2,5-diphenyl-1,3,4-oxadiazole derivatives  SHP2  Inhibitors  Structure-activity relationships (SAR)   BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 14 作者:  Feng, Mei;  Wu, Zhongen;  Zhou, Yan;  Wei, Zhuang;  Tian, Enming 收藏  |  浏览/下载：29/0  |  提交时间：2021/11/04 Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403 作者:  Li, Chunpu;  Hu, Sha-Sha;  Yang, Lisheng;  Wang, Min;  Long, Jian-Dong 收藏  |  浏览/下载：57/0  |  提交时间：2021/05/24 SIRT1  inhibitor  structure-activity relationship  interaction  deacetylase   One step stereoselective synthesis of oxazoline-fused saccharides and their conversion into the corresponding 1,2-cis glycosylamines bearing various protected groups 期刊论文 ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 7, 页码: 1580-1588 作者:  Dong, Sanfeng;  Zhao, Yitian;  Shi, Yulong;  Xu, Zhijian;  Shen, Jingshan 收藏  |  浏览/下载：13/0  |  提交时间：2021/05/24 Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文 CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18 作者:  Zhang, Ning;  Tian, Yu-Nan;  Zhou, Li-Na;  Li, Meng-Zhu;  Chen, Hua-Dong 收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24 Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文 Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1 作者:  Ning Zhang;  Yu-Nan Tian;  Li-Na Zhou 收藏  |  浏览/下载：18/0  |  提交时间：2021/12/01